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10.1074/jbc.R116.762906 http://scihub22266oqcxt.onion/10.1074/jbc.R116.762906 C5448083!5448083!28389564     free     free     free       J+Biol+Chem 2017 ; 292 (21): 8546-52 Nephropedia Template TP {{tp|p=28389564|t=2017. Natural product discovery from the human microbiome |pdf=|usr=}}{{28389564}} gab.com Text Natural product discovery from the human microbiome JO: J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=28389564 #FOAvip Human-associated microorganisms have the potential to biosynthesize numerous secondary metabolites that may mediate important host-microbe and microbe-microbe interactions. However, there is currently a limited understanding of microbiome-derived natural products. A variety of complementary discovery approaches have begun to illuminate this microbial ?dark matter,? which will in turn allow detailed mechanistic studies of the effects of these molecules on microbiome and host. Herein, we review recent efforts to uncover microbiome-derived natural products, describe the key approaches that were used to identify and characterize these metabolites, discuss potential functional roles of these molecules, and highlight challenges related to this emerging research area. Twit Text FOAVip Natural product discovery from the human microbiome ????J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=28389564 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28389564 #FOAvip English Wikipedia <ref>{{Cite pmid|28389564}}</ref> Natural product discovery from the human microbiome #MMPMID28389564 Wilson MR; Zha L; Balskus EP J Biol Chem 2017[May]; 292 (21): 8546-52 PMID28389564show ga Human-associated microorganisms have the potential to biosynthesize numerous secondary metabolites that may mediate important host-microbe and microbe-microbe interactions. However, there is currently a limited understanding of microbiome-derived natural products. A variety of complementary discovery approaches have begun to illuminate this microbial ?dark matter,? which will in turn allow detailed mechanistic studies of the effects of these molecules on microbiome and host. Herein, we review recent efforts to uncover microbiome-derived natural products, describe the key approaches that were used to identify and characterize these metabolites, discuss potential functional roles of these molecules, and highlight challenges related to this emerging research area. äNatural product discovery from the human microbiome (epmc).pdf DeepDyve Pubget Overpricing