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10.3389/fmed.2017.00066 http://scihub22266oqcxt.onion/10.3389/fmed.2017.00066 C5447724!5447724!28611987     free     free     free       Front+Med+(Lausanne) 2017 ; 4 (ä): ä Nephropedia Template TP {{tp|p=28611987|t=2017. Complement in Kidney Transplantation |pdf=|usr=}}{{28611987}} gab.com Text Complement in Kidney Transplantation JO: Front Med (Lausanne) http://www.kidney.de/pget.php?&tw=1&pmid=28611987 #FOAvip The complement system is considered to be an important part of innate immune system with a significant role in inflammation processes. The activation can occur through classical, alternative, or lectin pathway, resulting in the creation of anaphylatoxins C3a and C5a, possessing a vast spectrum of immune functions, and the assembly of terminal complement cascade, capable of direct cell lysis. The activation processes are tightly regulated; inappropriate activation of the complement cascade plays a significant role in many renal diseases including organ transplantation. Moreover, complement cascade is activated during ischemia/reperfusion injury processes and influences delayed graft function of kidney allografts. Interestingly, complement system has been found to play a role in both acute cellular and antibody-mediated rejections and thrombotic microangiopathy. Therefore, complement system may represent an interesting therapeutical target in kidney transplant pathologies. Twit Text FOAVip Complement in Kidney Transplantation ????Front Med (Lausanne) http://www.kidney.de/pget.php?&tw=1&pmid=28611987 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28611987 #FOAvip English Wikipedia <ref>{{Cite pmid|28611987}}</ref> Complement in Kidney Transplantation #MMPMID28611987 Cernoch M; Viklicky O Front Med (Lausanne) 2017[]; 4 (ä): ä PMID28611987show ga The complement system is considered to be an important part of innate immune system with a significant role in inflammation processes. The activation can occur through classical, alternative, or lectin pathway, resulting in the creation of anaphylatoxins C3a and C5a, possessing a vast spectrum of immune functions, and the assembly of terminal complement cascade, capable of direct cell lysis. The activation processes are tightly regulated; inappropriate activation of the complement cascade plays a significant role in many renal diseases including organ transplantation. Moreover, complement cascade is activated during ischemia/reperfusion injury processes and influences delayed graft function of kidney allografts. Interestingly, complement system has been found to play a role in both acute cellular and antibody-mediated rejections and thrombotic microangiopathy. Therefore, complement system may represent an interesting therapeutical target in kidney transplant pathologies. äComplement in Kidney Transplantation (epmc).pdf DeepDyve Pubget Overpricing