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10.1016/j.gde.2016.11.001 http://scihub22266oqcxt.onion/10.1016/j.gde.2016.11.001 C5447479!5447479!27940208     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Curr+Opin+Genet+Dev 2017 ; 43 (ä): 31-7 Nephropedia Template TP {{tp|p=27940208|t=2017. H3K27 methylation: a promiscuous repressive chromatin mark |pdf=|usr=}}{{27940208}} gab.com Text H3K27 methylation: a promiscuous repressive chromatin mark JO: Curr Opin Genet Dev http://www.kidney.de/pget.php?&tw=1&pmid=27940208 #FOAvip Polycomb Repressive Complex 2 (PRC2) is a multiprotein complex that catalyzes the methylation of lysine 27 on histone H3 (H3K27me). This histone modification is a feature of facultative heterochromatin in many eukaryotes and maintains transcriptional repression established during early development. Understanding how PRC2 targets regions of the genome to be methylated remains poorly understood. Different cell types can show disparate patterns of H3K27me, and chromatin perturbations, such as loss of marks of constitutive heterochromatin, can cause redistribution of H3K27me, implying that DNA sequence, per se, is not sufficient to define the distribution of this mark. Emerging information supports the idea that the chromatin context ? including histone modifications, DNA methylation, transcription, chromatin structure and organization within the nucleus ? informs PRC2 target selection. Twit Text FOAVip H3K27 methylation: a promiscuous repressive chromatin mark ????Curr Opin Genet Dev http://www.kidney.de/pget.php?&tw=1&pmid=27940208 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27940208 #FOAvip English Wikipedia <ref>{{Cite pmid|27940208}}</ref> H3K27 methylation: a promiscuous repressive chromatin mark #MMPMID27940208 Wiles ET; Selker EU Curr Opin Genet Dev 2017[Apr]; 43 (ä): 31-7 PMID27940208show ga Polycomb Repressive Complex 2 (PRC2) is a multiprotein complex that catalyzes the methylation of lysine 27 on histone H3 (H3K27me). This histone modification is a feature of facultative heterochromatin in many eukaryotes and maintains transcriptional repression established during early development. Understanding how PRC2 targets regions of the genome to be methylated remains poorly understood. Different cell types can show disparate patterns of H3K27me, and chromatin perturbations, such as loss of marks of constitutive heterochromatin, can cause redistribution of H3K27me, implying that DNA sequence, per se, is not sufficient to define the distribution of this mark. Emerging information supports the idea that the chromatin context ? including histone modifications, DNA methylation, transcription, chromatin structure and organization within the nucleus ? informs PRC2 target selection. äH3K27 methylation: a promiscuous repressive chromatin mark (epmc).pdf DeepDyve Pubget Overpricing