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10.1016/j.jsps.2017.05.001 http://scihub22266oqcxt.onion/10.1016/j.jsps.2017.05.001 C5447443!5447443 !28579909     free     free     free Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 249.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 249.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 249.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 249.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 249.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28579909 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Saudi+Pharm+J 2017 ; 25 (4 ): 666-670 Nephropedia Template TP {{tp|p=28579909 |t=2017. The alleviative effects of metformin for lipopolysaccharide-induced acute lung injury rat model and its underlying mechanism |pdf=|usr=}}{{28579909 }} gab.com Text The alleviative effects of metformin for lipopolysaccharide-induced acute lung injury rat model and its underlying mechanism JO: Saudi Pharm J http://www.kidney.de/pget.php?&tw=1&pmid=28579909 #FOAvip For patients who have sepsis, acute lung injury (ALI) causes most of death. Metformin (Met) is an anti-hyperglycemic agent and it has extensive pharmacological properties. This study aimed to analyze the influence of Met on lipopolysaccharide (LPS) -induced ALI. Met (1, 2, and 4 mg/kg) were injected and LPS was injected 30 min later. The data suggested Met can reduce release of inflammatory cytokines and bronchoalveolar lavage fluid (BALF) protein expression, reduce lung wet/dry ratio, and significantly improve LPS-induced lung destruction during ALI. In addition, Met inhibits LPS-induced neutrophil and macrophage infiltration, reduces MPO activity, and promotes AMPK-?1 expression in lung tissues. Our data suggested that metformin alleviates capillary injury during ALI via AMPK-?1. Twit Text FOAVip The alleviative effects of metformin for lipopolysaccharide-induced acute lung injury rat model and its underlying mechanism ????Saudi Pharm J http://www.kidney.de/pget.php?&tw=1&pmid=28579909 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28579909 #FOAvip English Wikipedia <ref>{{Cite pmid|28579909 }}</ref> The alleviative effects of metformin for lipopolysaccharide-induced acute lung injury rat model and its underlying mechanism #MMPMID28579909 Zhang X ; Shang F ; Hui L ; Zang K ; Sun G Saudi Pharm J 2017[May]; 25 (4 ): 666-670 PMID28579909 show ga For patients who have sepsis, acute lung injury (ALI) causes most of death. Metformin (Met) is an anti-hyperglycemic agent and it has extensive pharmacological properties. This study aimed to analyze the influence of Met on lipopolysaccharide (LPS) -induced ALI. Met (1, 2, and 4 mg/kg) were injected and LPS was injected 30 min later. The data suggested Met can reduce release of inflammatory cytokines and bronchoalveolar lavage fluid (BALF) protein expression, reduce lung wet/dry ratio, and significantly improve LPS-induced lung destruction during ALI. In addition, Met inhibits LPS-induced neutrophil and macrophage infiltration, reduces MPO activity, and promotes AMPK-?1 expression in lung tissues. Our data suggested that metformin alleviates capillary injury during ALI via AMPK-?1. äThe alleviative effects of metformin for lipopolysaccharide-induced ac(epmc).pdf DeepDyve Pubget Overpricing