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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Neurology
2017 ; 88
(22
): 2141-2149
Nephropedia Template TP
gab.com Text
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Twit Text #
English Wikipedia
Practice guideline summary: Reducing brain injury following cardiopulmonary
resuscitation: Report of the Guideline Development, Dissemination, and
Implementation Subcommittee of the American Academy of Neurology
#MMPMID28490655
Geocadin RG
; Wijdicks E
; Armstrong MJ
; Damian M
; Mayer SA
; Ornato JP
; Rabinstein A
; Suarez JI
; Torbey MT
; Dubinsky RM
; Lazarou J
Neurology
2017[May]; 88
(22
): 2141-2149
PMID28490655
show ga
OBJECTIVE: To assess the evidence and make evidence-based recommendations for
acute interventions to reduce brain injury in adult patients who are comatose
after successful cardiopulmonary resuscitation. METHODS: Published literature
from 1966 to August 29, 2016, was reviewed with evidence-based classification of
relevant articles. RESULTS AND RECOMMENDATIONS: For patients who are comatose in
whom the initial cardiac rhythm is either pulseless ventricular tachycardia (VT)
or ventricular fibrillation (VF) after out-of-hospital cardiac arrest (OHCA),
therapeutic hypothermia (TH; 32-34°C for 24 hours) is highly likely to be
effective in improving functional neurologic outcome and survival compared with
non-TH and should be offered (Level A). For patients who are comatose in whom the
initial cardiac rhythm is either VT/VF or asystole/pulseless electrical activity
(PEA) after OHCA, targeted temperature management (36°C for 24 hours, followed by
8 hours of rewarming to 37°C, and temperature maintenance below 37.5°C until 72
hours) is likely as effective as TH and is an acceptable alternative (Level B).
For patients who are comatose with an initial rhythm of PEA/asystole, TH possibly
improves survival and functional neurologic outcome at discharge vs standard care
and may be offered (Level C). Prehospital cooling as an adjunct to TH is highly
likely to be ineffective in further improving neurologic outcome and survival and
should not be offered (Level A). Other pharmacologic and nonpharmacologic
strategies (applied with or without concomitant TH) are also reviewed.
|Brain Injuries/*etiology/*prevention & control
[MESH]