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10.1016/j.cub.2017.02.061 http://scihub22266oqcxt.onion/10.1016/j.cub.2017.02.061 C5444402!5444402!28441569     free     free     free       Curr+Biol 2017 ; 27 (8): R318-26 Nephropedia Template TP {{tp|p=28441569|t=2017. The Cytoskeleton-Autophagy Connection |pdf=|usr=}}{{28441569}} gab.com Text The Cytoskeleton-Autophagy Connection JO: Curr Biol http://www.kidney.de/pget.php?&tw=1&pmid=28441569 #FOAvip Actin cytoskeleton dynamics plays vital roles in most forms of intracellular trafficking by promoting the biogenesis and transport of vesicular cargoes. Mounting evidence indicates that actin dynamics and membrane-cytoskeleton scaffolds also play essential roles in macroautophagy, the process by which cellular waste is isolated inside specialized vesicles called autophagosomes for recycling and degradation. Thus, branched-actin polymerization is necessary for the biogenesis of autophagosomes from the endoplasmic reticulum (ER) membrane. Actomyosin-based transport is then used to feed the growing phagophore with pre-selected cargoes and debris derived from different membranous organelles inside the cell. Mature autophagosomes then detach from the ER membrane by an unknown mechanism, and are transported and fused with lysosomes, endosomes and multi-vesicular bodies through mechanisms that involve actin- and microtubule-based motility, cytoskeleton-membrane scaffolds and signaling proteins. In this minireview, we highlight the considerable progress made recently towards understanding the diverse roles of the cytoskeleton in autophagy. Twit Text FOAVip The Cytoskeleton-Autophagy Connection ????Curr Biol http://www.kidney.de/pget.php?&tw=1&pmid=28441569 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28441569 #FOAvip English Wikipedia <ref>{{Cite pmid|28441569}}</ref> The Cytoskeleton-Autophagy Connection #MMPMID28441569 Kast DJ; Dominguez R Curr Biol 2017[Apr]; 27 (8): R318-26 PMID28441569show ga Actin cytoskeleton dynamics plays vital roles in most forms of intracellular trafficking by promoting the biogenesis and transport of vesicular cargoes. Mounting evidence indicates that actin dynamics and membrane-cytoskeleton scaffolds also play essential roles in macroautophagy, the process by which cellular waste is isolated inside specialized vesicles called autophagosomes for recycling and degradation. Thus, branched-actin polymerization is necessary for the biogenesis of autophagosomes from the endoplasmic reticulum (ER) membrane. Actomyosin-based transport is then used to feed the growing phagophore with pre-selected cargoes and debris derived from different membranous organelles inside the cell. Mature autophagosomes then detach from the ER membrane by an unknown mechanism, and are transported and fused with lysosomes, endosomes and multi-vesicular bodies through mechanisms that involve actin- and microtubule-based motility, cytoskeleton-membrane scaffolds and signaling proteins. In this minireview, we highlight the considerable progress made recently towards understanding the diverse roles of the cytoskeleton in autophagy. äThe Cytoskeleton-Autophagy Connection (epmc).pdf DeepDyve Pubget Overpricing