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10.1164/rccm.201411-2094CI

http://scihub22266oqcxt.onion/10.1164/rccm.201411-2094CI
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C5442966!5442966!25906089
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suck abstract from ncbi

pmid25906089      Am+J+Respir+Crit+Care+Med 2015 ; 191 (12): 1354-66
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  • Diffuse Cystic Lung Disease Part I #MMPMID25906089
  • Gupta N; Vassallo R; Wikenheiser-Brokamp KA; McCormack FX
  • Am J Respir Crit Care Med 2015[Jun]; 191 (12): 1354-66 PMID25906089show ga
  • The diffuse cystic lung diseases (DCLDs) are a group of pathophysiologically heterogenous processes that are characterized by the presence of multiple spherical or irregularly shaped, thin-walled, air-filled spaces within the pulmonary parenchyma. Although the mechanisms of cyst formation remain incompletely defined for all DCLDs, in most cases lung remodeling associated with inflammatory or infiltrative processes results in displacement, destruction, or replacement of alveolar septa, distal airways, and small vessels within the secondary lobules of the lung. The DCLDs can be broadly classified according to underlying etiology as those caused by low-grade or high-grade metastasizing neoplasms, polyclonal or monoclonal lymphoproliferative disorders, infections, interstitial lung diseases, smoking, and congenital or developmental defects. In the first of a two-part series, we present an overview of the cystic lung diseases caused by neoplasms, infections, smoking-related diseases, and interstitial lung diseases, with a focus on lymphangioleiomyomatosis and pulmonary Langerhans cell histiocytosis.
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