Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1016/j.bone.2016.11.025 http://scihub22266oqcxt.onion/10.1016/j.bone.2016.11.025 C5441975!5441975!27890549     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27890549&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Bone 2017 ; 100 (ä): 36-40 Nephropedia Template TP {{tp|p=27890549|t=2017. Novel functions of circulating Klotho |pdf=|usr=}}{{27890549}} gab.com Text Novel functions of circulating Klotho JO: Bone http://www.kidney.de/pget.php?&tw=1&pmid=27890549 #FOAvip A significant portion of the key biological functions of ?Klotho (?KL) and its cognate ligand Fibroblast growth factor-23 (FGF23) have been revealed through the study of rare diseases of mineral metabolism. These findings have far reaching implications for common disorders such as chronic kidney disease-mineral bone disorder (CKD-MBD). ?KL?s predominant effect on mineral homeostasis is through its actions in the kidney as a co-receptor for FGF23, however emerging data has shed light on its capacity to act as a circulating factor through the cleavage of the transmembrane form of ?KL (?mKL?) to produce ?cleaved KL? or ?cKL?. This review summarizes new findings from studies using extended delivery of cKL to mouse models with phenotypes reflecting those arising in CKD-MBD. Twit Text FOAVip Novel functions of circulating Klotho ????Bone http://www.kidney.de/pget.php?&tw=1&pmid=27890549 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27890549 #FOAvip English Wikipedia <ref>{{Cite pmid|27890549}}</ref> Novel functions of circulating Klotho #MMPMID27890549 Hum JM; O?Bryan L; Smith RC; White KE Bone 2017[Jul]; 100 (ä): 36-40 PMID27890549show ga A significant portion of the key biological functions of ?Klotho (?KL) and its cognate ligand Fibroblast growth factor-23 (FGF23) have been revealed through the study of rare diseases of mineral metabolism. These findings have far reaching implications for common disorders such as chronic kidney disease-mineral bone disorder (CKD-MBD). ?KL?s predominant effect on mineral homeostasis is through its actions in the kidney as a co-receptor for FGF23, however emerging data has shed light on its capacity to act as a circulating factor through the cleavage of the transmembrane form of ?KL (?mKL?) to produce ?cleaved KL? or ?cKL?. This review summarizes new findings from studies using extended delivery of cKL to mouse models with phenotypes reflecting those arising in CKD-MBD. äNovel functions of circulating Klotho (epmc).pdf DeepDyve Pubget Overpricing