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10.1016/j.jclinepi.2017.01.011 http://scihub22266oqcxt.onion/10.1016/j.jclinepi.2017.01.011 C5441956!5441956 !28188899     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28188899 &cmd=llinks): Failed to open stream: HTTP request failed! 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Publication of comparative effectiveness research has not increased in high-impact medical journals, 2004-2013 |pdf=|usr=}}{{28188899 }} gab.com Text Publication of comparative effectiveness research has not increased in high-impact medical journals, 2004-2013 JO: J Clin Epidemiol http://www.kidney.de/pget.php?&tw=1&pmid=28188899 #FOAvip OBJECTIVE: To explore the impact of increasing interest and investment in patient-centered research, this study sought to describe patterns of comparative effectiveness research (CER) and patient-reported outcomes (PROs) in pharmacologic intervention studies published in widely read medical journals from 2004-2013. DESIGN AND SETTING: We identified 2335 articles published in five widely read medical journals from 2004-2013 with ?1 intervention meeting the US Food and Drug Administration's definitions for a drug, biologic, or vaccine. Six trained reviewers extracted characteristics from a 20% random sample of articles (468 studies). We calculated the proportion of studies with CER and PROs. Trends were summarized using locally-weighted means and 95% confidence intervals. RESULTS: Of the 468 sampled studies, 30% used CER designs and 33% assessed PROs. The proportion of studies using CER designs did not meaningfully increase over the study period. However, we observed an increase in the use of PROs. CONCLUSIONS: Among pharmacological intervention studies published in widely read medical journals from 2004-2013, we identified no increase in CER. Randomized, placebo-controlled trials continue to be the dominant study design for assessing pharmacologic interventions. Increasing trends in PRO use may indicate greater acceptance of these outcomes as evidence for clinical benefit. Twit Text FOAVip Publication of comparative effectiveness research has not increased in high-impact medical journals, 2004-2013 ????J Clin Epidemiol http://www.kidney.de/pget.php?&tw=1&pmid=28188899 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28188899 #FOAvip English Wikipedia <ref>{{Cite pmid|28188899 }}</ref> Publication of comparative effectiveness research has not increased in high-impact medical journals, 2004-2013 #MMPMID28188899 Hester LL ; Poole C ; Suarez EA ; Der JS ; Anderson OG ; Almon KG ; Shirke AV ; Brookhart MA J Clin Epidemiol 2017[Apr]; 84 (ä): 185-187 PMID28188899 show ga OBJECTIVE: To explore the impact of increasing interest and investment in patient-centered research, this study sought to describe patterns of comparative effectiveness research (CER) and patient-reported outcomes (PROs) in pharmacologic intervention studies published in widely read medical journals from 2004-2013. DESIGN AND SETTING: We identified 2335 articles published in five widely read medical journals from 2004-2013 with ?1 intervention meeting the US Food and Drug Administration's definitions for a drug, biologic, or vaccine. Six trained reviewers extracted characteristics from a 20% random sample of articles (468 studies). We calculated the proportion of studies with CER and PROs. Trends were summarized using locally-weighted means and 95% confidence intervals. RESULTS: Of the 468 sampled studies, 30% used CER designs and 33% assessed PROs. The proportion of studies using CER designs did not meaningfully increase over the study period. However, we observed an increase in the use of PROs. CONCLUSIONS: Among pharmacological intervention studies published in widely read medical journals from 2004-2013, we identified no increase in CER. Randomized, placebo-controlled trials continue to be the dominant study design for assessing pharmacologic interventions. Increasing trends in PRO use may indicate greater acceptance of these outcomes as evidence for clinical benefit. |*Research Design [MESH] |Comparative Effectiveness Research/methods/*statistics & numerical data [MESH] |Humans [MESH]Publication of comparative effectiveness research has not increased in(epmc).pdf DeepDyve Pubget Overpricing