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10.1097/TP.0000000000001211 http://scihub22266oqcxt.onion/10.1097/TP.0000000000001211 C5441890!5441890 !27257998     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27257998 &cmd=llinks): Failed to open stream: HTTP request failed! 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Similar 5-Year Estimated Glomerular Filtration Rate Between Kidney Transplants From Uncontrolled and Controlled Donors After Circulatory Death-A Dutch Cohort Study |pdf=|usr=}}{{27257998 }} gab.com Text Similar 5-Year Estimated Glomerular Filtration Rate Between Kidney Transplants From Uncontrolled and Controlled Donors After Circulatory Death-A Dutch Cohort Study JO: Transplantation http://www.kidney.de/pget.php?&tw=1&pmid=27257998 #FOAvip BACKGROUND: Organ shortage persists despite a high rate of donation after circulatory death (DCD) in the Netherlands. The median waiting time for a deceased donor kidney in 2013 was 3.5 years. Most DCD kidneys are from controlled DCD (cDCD; Maastricht category III). Experience with uncontrolled donors after cardiac death (uDCD), that is, donors with an unexpected and irreversible cardiac arrest (Maastricht categories I and II), is increasing; and its effect on transplant outcomes needs evaluation. METHODS: We used the Dutch Organ Transplantation Registry to include recipients (?18 years old) from all Dutch centers who received transplants from 2002 to 2012 with a first DCD kidney. We compared transplant outcome in uDCD (n = 97) and cDCD (n = 1441). RESULTS: Primary nonfunction in uDCD was higher than in the cDCD (19.6% vs 9.6%, P < 0.001, respectively). Delayed graft function was also higher in uDCD than in cDCD, but not significantly (73.7% vs 63.3%, P = .074, respectively). If censored for primary nonfunction, estimated glomerular filtration rates after 1 year and 5 years were comparable between uDCD and cDCD (1 year: uDCD, 44.3 (23.4) mL/min/m and cDCD, 45.8 (24.1) mL/min/m; P = 0.621; 5 years: uDCD, 49.1 (25.6) mL/min/m and cDCD, 47.7 (21.7) mL/min/m; P = 0.686). The differences in primary nonfunction between kidneys from uDCD and cDCD were explained by differences in the first warm ischemic period, cold ischemic time, and donor age. CONCLUSIONS: We conclude that uDCD kidneys have potential for excellent function and can constitute a valuable extension of the donor pool. However, further efforts are necessary to address the high rate of primary nonfunction. Twit Text FOAVip Similar 5-Year Estimated Glomerular Filtration Rate Between Kidney Transplants From Uncontrolled and Controlled Donors After Circulatory Death-A Dutch Cohort Study ????Transplantation http://www.kidney.de/pget.php?&tw=1&pmid=27257998 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27257998 #FOAvip English Wikipedia <ref>{{Cite pmid|27257998 }}</ref> Similar 5-Year Estimated Glomerular Filtration Rate Between Kidney Transplants From Uncontrolled and Controlled Donors After Circulatory Death-A Dutch Cohort Study #MMPMID27257998 Peters-Sengers H ; Homan van der Heide JJ ; Heemskerk MBA ; Ten Berge IJM ; Ultee FCW ; Idu MM ; Betjes MGH ; van Zuilen AD ; Christiaans MHL ; Hilbrands LH ; de Vries APJ ; Nurmohamed AS ; Berger SP ; Bemelman FJ Transplantation 2017[Jun]; 101 (6 ): 1144-1151 PMID27257998 show ga BACKGROUND: Organ shortage persists despite a high rate of donation after circulatory death (DCD) in the Netherlands. The median waiting time for a deceased donor kidney in 2013 was 3.5 years. Most DCD kidneys are from controlled DCD (cDCD; Maastricht category III). Experience with uncontrolled donors after cardiac death (uDCD), that is, donors with an unexpected and irreversible cardiac arrest (Maastricht categories I and II), is increasing; and its effect on transplant outcomes needs evaluation. METHODS: We used the Dutch Organ Transplantation Registry to include recipients (?18 years old) from all Dutch centers who received transplants from 2002 to 2012 with a first DCD kidney. We compared transplant outcome in uDCD (n = 97) and cDCD (n = 1441). RESULTS: Primary nonfunction in uDCD was higher than in the cDCD (19.6% vs 9.6%, P < 0.001, respectively). Delayed graft function was also higher in uDCD than in cDCD, but not significantly (73.7% vs 63.3%, P = .074, respectively). If censored for primary nonfunction, estimated glomerular filtration rates after 1 year and 5 years were comparable between uDCD and cDCD (1 year: uDCD, 44.3 (23.4) mL/min/m and cDCD, 45.8 (24.1) mL/min/m; P = 0.621; 5 years: uDCD, 49.1 (25.6) mL/min/m and cDCD, 47.7 (21.7) mL/min/m; P = 0.686). The differences in primary nonfunction between kidneys from uDCD and cDCD were explained by differences in the first warm ischemic period, cold ischemic time, and donor age. CONCLUSIONS: We conclude that uDCD kidneys have potential for excellent function and can constitute a valuable extension of the donor pool. However, further efforts are necessary to address the high rate of primary nonfunction. |*Donor Selection [MESH] |*Glomerular Filtration Rate [MESH] |Adult [MESH] |Cardiovascular Diseases/diagnosis/*mortality [MESH] |Cause of Death [MESH] |Female [MESH] |Graft Survival [MESH] |Humans [MESH] |Kaplan-Meier Estimate [MESH] |Kidney Transplantation/adverse effects/*methods [MESH] |Kidney/*physiopathology/*surgery [MESH] |Male [MESH] |Middle Aged [MESH] |Netherlands [MESH] |Primary Graft Dysfunction/etiology/physiopathology [MESH] |Registries [MESH] |Risk Factors [MESH] |Time Factors [MESH] |Tissue Donors/*supply & distribution [MESH]Similar 5-Year Estimated Glomerular Filtration Rate Between Kidney Tra(epmc).pdf DeepDyve Pubget Overpricing