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10.1186/s12967-017-1218-4

http://scihub22266oqcxt.onion/10.1186/s12967-017-1218-4
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suck abstract from ncbi


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pmid28532423
      J+Transl+Med 2017 ; 15 (1 ): 110
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  • The various aspects of genetic and epigenetic toxicology: testing methods and clinical applications #MMPMID28532423
  • Ren N ; Atyah M ; Chen WY ; Zhou CH
  • J Transl Med 2017[May]; 15 (1 ): 110 PMID28532423 show ga
  • Genotoxicity refers to the ability of harmful substances to damage genetic information in cells. Being exposed to chemical and biological agents can result in genomic instabilities and/or epigenetic alterations, which translate into a variety of diseases, cancer included. This concise review discusses, from both a genetic and epigenetic point of view, the current detection methods of different agents' genotoxicity, along with their basic and clinical relation to human cancer, chemotherapy, germ cells and stem cells.
  • |*Epigenesis, Genetic [MESH]
  • |Animals [MESH]
  • |Comet Assay [MESH]
  • |Germ Cells/metabolism [MESH]
  • |Humans [MESH]
  • |Neoplasms/drug therapy/genetics [MESH]
  • |Stem Cells/metabolism [MESH]


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