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10.3389/fimmu.2017.00598 http://scihub22266oqcxt.onion/10.3389/fimmu.2017.00598 C5440529!5440529!28588585     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Immunol 2017 ; 8 (ä): ä Nephropedia Template TP {{tp|p=28588585|t=2017. Leaky Gut As a Danger Signal for Autoimmune Diseases |pdf=|usr=}}{{28588585}} gab.com Text Leaky Gut As a Danger Signal for Autoimmune Diseases JO: Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=28588585 #FOAvip The intestinal epithelial lining, together with factors secreted from it, forms a barrier that separates the host from the environment. In pathologic conditions, the permeability of the epithelial lining may be compromised allowing the passage of toxins, antigens, and bacteria in the lumen to enter the blood stream creating a ?leaky gut.? In individuals with a genetic predisposition, a leaky gut may allow environmental factors to enter the body and trigger the initiation and development of autoimmune disease. Growing evidence shows that the gut microbiota is important in supporting the epithelial barrier and therefore plays a key role in the regulation of environmental factors that enter the body. Several recent reports have shown that probiotics can reverse the leaky gut by enhancing the production of tight junction proteins; however, additional and longer term studies are still required. Conversely, pathogenic bacteria that can facilitate a leaky gut and induce autoimmune symptoms can be ameliorated with the use of antibiotic treatment. Therefore, it is hypothesized that modulating the gut microbiota can serve as a potential method for regulating intestinal permeability and may help to alter the course of autoimmune diseases in susceptible individuals. Twit Text FOAVip Leaky Gut As a Danger Signal for Autoimmune Diseases ????Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=28588585 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28588585 #FOAvip English Wikipedia <ref>{{Cite pmid|28588585}}</ref> Leaky Gut As a Danger Signal for Autoimmune Diseases #MMPMID28588585 Mu Q; Kirby J; Reilly CM; Luo XM Front Immunol 2017[]; 8 (ä): ä PMID28588585show ga The intestinal epithelial lining, together with factors secreted from it, forms a barrier that separates the host from the environment. In pathologic conditions, the permeability of the epithelial lining may be compromised allowing the passage of toxins, antigens, and bacteria in the lumen to enter the blood stream creating a ?leaky gut.? In individuals with a genetic predisposition, a leaky gut may allow environmental factors to enter the body and trigger the initiation and development of autoimmune disease. Growing evidence shows that the gut microbiota is important in supporting the epithelial barrier and therefore plays a key role in the regulation of environmental factors that enter the body. Several recent reports have shown that probiotics can reverse the leaky gut by enhancing the production of tight junction proteins; however, additional and longer term studies are still required. Conversely, pathogenic bacteria that can facilitate a leaky gut and induce autoimmune symptoms can be ameliorated with the use of antibiotic treatment. Therefore, it is hypothesized that modulating the gut microbiota can serve as a potential method for regulating intestinal permeability and may help to alter the course of autoimmune diseases in susceptible individuals. äLeaky Gut As a Danger Signal for Autoimmune Diseases (epmc).pdf DeepDyve Pubget Overpricing