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10.1038/s41598-017-02346-3 http://scihub22266oqcxt.onion/10.1038/s41598-017-02346-3 C5440373!5440373!28533504     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2017 ; 7 (ä): ä Nephropedia Template TP {{tp|p=28533504|t=2017. Identification of genetic loci shared between schizophrenia and the Big Five personality traits |pdf=|usr=}}{{28533504}} gab.com Text Identification of genetic loci shared between schizophrenia and the Big Five personality traits JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=28533504 #FOAvip Schizophrenia is associated with differences in personality traits, and recent studies suggest that personality traits and schizophrenia share a genetic basis. Here we aimed to identify specific genetic loci shared between schizophrenia and the Big Five personality traits using a Bayesian statistical framework. Using summary statistics from genome-wide association studies (GWAS) on personality traits in the 23andMe cohort (n?=?59,225) and schizophrenia in the Psychiatric Genomics Consortium cohort (n?=?82,315), we evaluated overlap in common genetic variants. The Big Five personality traits neuroticism, extraversion, openness, agreeableness and conscientiousness were measured using a web implementation of the Big Five Inventory. Applying the conditional false discovery rate approach, we increased discovery of genetic loci and identified two loci shared between neuroticism and schizophrenia and six loci shared between openness and schizophrenia. The study provides new insights into the relationship between personality traits and schizophrenia by highlighting genetic loci involved in their common genetic etiology. Twit Text FOAVip Identification of genetic loci shared between schizophrenia and the Big Five personality traits ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=28533504 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28533504 #FOAvip English Wikipedia <ref>{{Cite pmid|28533504}}</ref> Identification of genetic loci shared between schizophrenia and the Big Five personality traits #MMPMID28533504 Smeland OB; Wang Y; Lo MT; Li W; Frei O; Witoelar A; Tesli M; Hinds DA; Tung JY; Djurovic S; Chen CH; Dale AM; Andreassen OA Sci Rep 2017[]; 7 (ä): ä PMID28533504show ga Schizophrenia is associated with differences in personality traits, and recent studies suggest that personality traits and schizophrenia share a genetic basis. Here we aimed to identify specific genetic loci shared between schizophrenia and the Big Five personality traits using a Bayesian statistical framework. Using summary statistics from genome-wide association studies (GWAS) on personality traits in the 23andMe cohort (n?=?59,225) and schizophrenia in the Psychiatric Genomics Consortium cohort (n?=?82,315), we evaluated overlap in common genetic variants. The Big Five personality traits neuroticism, extraversion, openness, agreeableness and conscientiousness were measured using a web implementation of the Big Five Inventory. Applying the conditional false discovery rate approach, we increased discovery of genetic loci and identified two loci shared between neuroticism and schizophrenia and six loci shared between openness and schizophrenia. The study provides new insights into the relationship between personality traits and schizophrenia by highlighting genetic loci involved in their common genetic etiology. äIdentification of genetic loci shared between schizophrenia and the Bi(epmc).pdf DeepDyve Pubget Overpricing