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2014 ; 7
(4
): 336-41
Nephropedia Template TP
gab.com Text
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English Wikipedia
Development and maintenance of a biospecimen repository for clinical samples
derived from pulmonary patients
#MMPMID24889057
Schwiebert LM
; Estell K
; Meadows T
; Thannickal VJ
; Rowe S
; Sorscher EJ
; Harris WT
; Gaggar A
; Dransfield M
; de Andrade JA
Clin Transl Sci
2014[Aug]; 7
(4
): 336-41
PMID24889057
show ga
The Pulmonary Biospecimen Repository (PBR) at the University of Alabama at
Birmingham (UAB) was launched in 2009. The purpose of the UAB PBR is to provide
investigators within the pulmonary community at UAB and elsewhere with clinical
samples derived from multiple lung diseases, including transplant recipients,
idiopathic pulmonary fibrosis, chronic obstructive pulmonary disease, cystic
fibrosis, and asthma. Cell and fluid samples isolated from bronchoalveolar lavage
(BAL), plasma, and serum are collected and stored; samples are assessed routinely
for viability. Each sample is linked directly with the respective patient
information via the Pulmonary Translational Research and Clinical Database, a
Health Insurance Portability and Accountability Act compliant database that
includes detailed information allowing for the study of specific patient cohorts.
To access samples, investigators must complete a request form, which is reviewed
by the UAB PBR Steering Committee. To date, more than 800 patients have provided
approximately 7,000 BAL, serum and plasma fluid, and cell samples. Over the past
4 years, nearly 800 of these samples have been distributed to investigators at
UAB and elsewhere. Future plans for the UAB PBR include expanding sample
collection to additional pulmonary diseases, such as mycobacterial infections,
increasing the number of sample users and obtaining external funding to ensure
its continued sustainability.
|*Biological Specimen Banks/supply & distribution
[MESH]