Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28195568
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Transl+Psychiatry
2017 ; 7
(2
): e1031
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Military deployment correlates with smaller prefrontal gray matter volume and
psychological symptoms in a subclinical population
#MMPMID28195568
Butler O
; Adolf J
; Gleich T
; Willmund G
; Zimmermann P
; Lindenberger U
; Gallinat J
; Kühn S
Transl Psychiatry
2017[Feb]; 7
(2
): e1031
PMID28195568
show ga
Research investigating the effects of trauma exposure on brain structure and
function in adults has mainly focused on post-traumatic stress disorder (PTSD),
whereas trauma-exposed individuals without a clinical diagnoses often serve as
controls. However, this assumes a dichotomy between clinical and subclinical
populations that may not be supported at the neural level. In the current study
we investigate whether the effects of repeated or long-term stress exposure on
brain structure in a subclinical sample are similar to previous PTSD neuroimaging
findings. We assessed 27 combat trauma-exposed individuals by means of
whole-brain voxel-based morphometry on 3?T magnetic resonance imaging scans and
identified a negative association between duration of military deployment and
gray matter volumes in ventromedial prefrontal cortex (vmPFC) and dorsal anterior
cingulate cortex (ACC). We also found a negative relationship between
deployment-related gray matter volumes and psychological symptoms, but not
between military deployment and psychological symptoms. To our knowledge, this is
the first whole-brain analysis showing that longer military deployment is
associated with smaller regional brain volumes in combat-exposed individuals
without PTSD. Notably, the observed gray matter associations resemble those
previously identified in PTSD populations, and concern regions involved in
emotional regulation and fear extinction. These findings question the current
dichotomy between clinical and subclinical populations in PTSD neuroimaging
research. Instead, neural correlates of both stress exposure and PTSD
symptomatology may be more meaningfully investigated at a continuous level.
free
free
free
