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10.1007/s40620-016-0366-6

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suck abstract from ncbi


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pmid27900718
      J+Nephrol 2017 ; 30 (3 ): 441-447
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  • Survival and time-to-transplantation of peritoneal dialysis versus hemodialysis for end-stage renal disease patients: competing-risks regression model in a single Italian center experience #MMPMID27900718
  • Rigoni M ; Torri E ; Nollo G ; Zarantonello D ; Laudon A ; Sottini L ; Guarrera GM ; Brunori G
  • J Nephrol 2017[Jun]; 30 (3 ): 441-447 PMID27900718 show ga
  • AIMS: Despite several studies reporting similar outcomes for peritoneal dialysis (PD) and hemodialysis (HD), the former is underused worldwide, with a PD prevalence of 15% in Italy. In 2008, the Unit of Nephrology and Dialysis of the Healthcare Trust of the Autonomous Province of Trento implemented a successful PD program which has increased the proportion of PD incident patients from 7 to 47%. We aimed to assess the effect of this extensive use of PD by comparing HD and PD in terms of survival and time-to-transplantation. METHODS: A total of 334 HD and 153 PD incident patients were enrolled between January 2008 and December 2014. After screening for exclusion criteria and propensity score matching, 279 HD and 132 PD patients were analyzed. Survival and time-to-transplantation were assessed by competing-risks regression models, using death and transplantation as primary and competing events. RESULTS: Crude and adjusted regression models for survival revealed the absence of significant differences between HD and PD cumulative incidence functions (subhazard ratio: 1.09, p?=?0.62 and 1.34, p?=?0.10, respectively). Differently, crude and adjusted regression models for transplantation revealed a lower time-to-transplantation for PD versus HD patients (subhazard ratio: 2.34, p?
  • |*Kidney Transplantation/adverse effects/mortality [MESH]
  • |*Peritoneal Dialysis/adverse effects/mortality [MESH]
  • |*Renal Dialysis/adverse effects/mortality [MESH]
  • |*Time-to-Treatment [MESH]
  • |Aged [MESH]
  • |Female [MESH]
  • |Humans [MESH]
  • |Italy [MESH]
  • |Kidney Failure, Chronic/diagnosis/mortality/surgery/*therapy [MESH]
  • |Male [MESH]
  • |Middle Aged [MESH]
  • |Propensity Score [MESH]
  • |Regression Analysis [MESH]
  • |Retrospective Studies [MESH]
  • |Risk Assessment [MESH]
  • |Risk Factors [MESH]
  • |Time Factors [MESH]


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