Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28545062
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 PLoS+One
2017 ; 12
(5
): e0177157
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Association of frailty status with acute kidney injury and mortality after
transcatheter aortic valve replacement: A systematic review and meta-analysis
#MMPMID28545062
Thongprayoon C
; Cheungpasitporn W
; Thamcharoen N
; Ungprasert P
; Kittanamongkolchai W
; Mao MA
; Sakhuja A
; Greason KL
; Kashani K
PLoS One
2017[]; 12
(5
): e0177157
PMID28545062
show ga
OBJECTIVE: Frailty is a common condition in patients with severe aortic stenosis
(AS) undergoing transcatheter aortic valve replacement (TAVR). The aim of this
systematic review was to assess the impact of frailty status on acute kidney
injury (AKI) and mortality after TAVR. METHODS: A systematic literature search
was conducted using MEDLINE, EMBASE, and Cochrane databases from the inception
through November 2016. The protocol for this study is registered with PROSPERO
(International Prospective Register of Systematic Reviews; no. CRD42016052350).
Studies that reported odds ratios, relative risks or hazard ratios comparing the
risk of AKI after TAVR in frail vs. non-frail patients were included. Mortality
risk was evaluated among the studies that reported AKI-related outcomes. Pooled
risk ratios (RR) and 95% confidence interval (CI) were calculated using a
random-effect, generic inverse variance method. RESULTS: Eight cohort studies
with a total of 10,498 patients were identified and included in the
meta-analysis. The pooled RR of AKI after TAVR among the frail patients was 1.19
(95% CI 0.97-1.46, I2 = 0), compared with non-frail patients. When the
meta-analysis was restricted only to studies with standardized AKI diagnosis
according to Valve Academic Research Consortium (VARC)-2 criteria, the pooled RRs
of AKI in frail patients was 1.16 (95% CI 0.91-1.47, I2 = 0). Within the selected
studies, frailty status was significantly associated with increased mortality (RR
2.01; 95% CI 1.44-2.80, I2 = 58). CONCLUSION: The findings from our study suggest
no significant association between frailty status and AKI after TAVR. However,
frailty status is associated with mortality after TAVR and may aid appropriate
patient selection for TAVR.