Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1007/s12026-011-8212-3 http://scihub22266oqcxt.onion/10.1007/s12026-011-8212-3 C5436281!5436281!21717083     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Immunol+Res 2011 ; 50 (2-3): 118-23 Nephropedia Template TP {{tp|p=21717083|t=2011. Macrophage Responses to Bacterial Toxins: a balance between activation and suppression |pdf=|usr=}}{{21717083}} gab.com Text Macrophage Responses to Bacterial Toxins: a balance between activation and suppression JO: Immunol Res http://www.kidney.de/pget.php?&tw=1&pmid=21717083 #FOAvip Toxins secreted by bacteria can impact the host in a number of different ways. In some infections, toxins play a crucial and central role in pathogenesis (i.e. anthrax), while in other bacterial infections, the role of toxins is less understood. The cholesterol-dependent cytolysins (CDCs), of which streptolysin O is a prototype, are a class of pore-forming toxins produced by many Gram positive bacteria and have only been studied in a few experimental infection models. Our laboratory has demonstrated that CDCs have effects on macrophages that are both pro-and anti-inflammatory. Here we review evidence that CDCs promote inflammation by driving the secretion of IL-1? and HMGB-1 from macrophages in a NLRP3 dependent manner, while also causing shedding of membrane microvesicles from cells that can interact with macrophages and inhibit TNF-? release. CDCs thus impact macrophage function in ways that may be both beneficial and detrimental to the host. Twit Text FOAVip Macrophage Responses to Bacterial Toxins: a balance between activation and suppression ????Immunol Res http://www.kidney.de/pget.php?&tw=1&pmid=21717083 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=21717083 #FOAvip English Wikipedia <ref>{{Cite pmid|21717083}}</ref> Macrophage Responses to Bacterial Toxins: a balance between activation and suppression #MMPMID21717083 Keyel PA; Heid ME; Salter RD Immunol Res 2011[Aug]; 50 (2-3): 118-23 PMID21717083show ga Toxins secreted by bacteria can impact the host in a number of different ways. In some infections, toxins play a crucial and central role in pathogenesis (i.e. anthrax), while in other bacterial infections, the role of toxins is less understood. The cholesterol-dependent cytolysins (CDCs), of which streptolysin O is a prototype, are a class of pore-forming toxins produced by many Gram positive bacteria and have only been studied in a few experimental infection models. Our laboratory has demonstrated that CDCs have effects on macrophages that are both pro-and anti-inflammatory. Here we review evidence that CDCs promote inflammation by driving the secretion of IL-1? and HMGB-1 from macrophages in a NLRP3 dependent manner, while also causing shedding of membrane microvesicles from cells that can interact with macrophages and inhibit TNF-? release. CDCs thus impact macrophage function in ways that may be both beneficial and detrimental to the host. äMacrophage Responses to Bacterial Toxins: a balance between activation(epmc).pdf DeepDyve Pubget Overpricing