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10.1002/eji.201646681 http://scihub22266oqcxt.onion/10.1002/eji.201646681 C5435927!5435927!28295233     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Eur+J+Immunol 2017 ; 47 (5): 860-71 Nephropedia Template TP {{tp|p=28295233|t=2017. Retention of Ag?specific memory CD4+ T cells in the draining lymph node indicates lymphoid tissue resident memory populations |pdf=|usr=}}{{28295233}} gab.com Text Retention of Ag specific memory CD4+ T cells in the draining lymph node indicates lymphoid tissue resident memory populations JO: Eur J Immunol http://www.kidney.de/pget.php?&tw=1&pmid=28295233 #FOAvip Several different memory T?cell populations have now been described based upon surface receptor expression and migratory capabilities. Here we have assessed murine endogenous memory CD4+ T cells generated within a draining lymph node and their subsequent migration to other secondary lymphoid tissues. Having established a model response targeting a specific peripheral lymph node, we temporally labelled all the cells within draining lymph node using photoconversion. Tracking of photoconverted and non?photoconverted Ag?specific CD4+ T cells revealed the rapid establishment of a circulating memory population in all lymph nodes within days of immunisation. Strikingly, a resident memory CD4+ T cell population became established in the draining lymph node and persisted for several months in the absence of detectable migration to other lymphoid tissue. These cells most closely resembled effector memory T cells, usually associated with circulation through non?lymphoid tissue, but here, these cells were retained in the draining lymph node. These data indicate that lymphoid tissue resident memory CD4+ T?cell populations are generated in peripheral lymph nodes following immunisation. Twit Text FOAVip Retention of Ag specific memory CD4+ T cells in the draining lymph node indicates lymphoid tissue resident memory populations ????Eur J Immunol http://www.kidney.de/pget.php?&tw=1&pmid=28295233 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28295233 #FOAvip English Wikipedia <ref>{{Cite pmid|28295233}}</ref> Retention of Ag?specific memory CD4+ T cells in the draining lymph node indicates lymphoid tissue resident memory populations #MMPMID28295233 Marriott CL; Dutton EE; Tomura M; Withers DR Eur J Immunol 2017[May]; 47 (5): 860-71 PMID28295233show ga Several different memory T?cell populations have now been described based upon surface receptor expression and migratory capabilities. Here we have assessed murine endogenous memory CD4+ T cells generated within a draining lymph node and their subsequent migration to other secondary lymphoid tissues. Having established a model response targeting a specific peripheral lymph node, we temporally labelled all the cells within draining lymph node using photoconversion. Tracking of photoconverted and non?photoconverted Ag?specific CD4+ T cells revealed the rapid establishment of a circulating memory population in all lymph nodes within days of immunisation. Strikingly, a resident memory CD4+ T cell population became established in the draining lymph node and persisted for several months in the absence of detectable migration to other lymphoid tissue. These cells most closely resembled effector memory T cells, usually associated with circulation through non?lymphoid tissue, but here, these cells were retained in the draining lymph node. These data indicate that lymphoid tissue resident memory CD4+ T?cell populations are generated in peripheral lymph nodes following immunisation. äRetention of Ag?specific memory CD4+ T cells in the draining lymph nod(epmc).pdf DeepDyve Pubget Overpricing