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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Neth+Heart+J
2017 ; 25
(6
): 370-375
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Clinical characteristics of patients with suspected cardiac chest pain and
angiographically normal coronary arteries in a secondary care hospital
#MMPMID28429135
de Lange TS
; Tijssen RYG
; Damman P
; van Bergen PFMM
Neth Heart J
2017[Jun]; 25
(6
): 370-375
PMID28429135
show ga
BACKGROUND: An important number of patients with suspected cardiac chest pain
have non-obstructive coronary artery disease. Our purpose was to describe the
clinical characteristics of patients with normal or near-normal coronary arteries
in routine cardiological practice in a secondary care hospital. METHODS: In 2013,
consecutive patients referred for invasive coronary angiography with suspected
cardiac chest pain were analysed at a single-centre (Westfriesgasthuis, Hoorn,
the Netherlands). Coronary arteries were defined as normal or near-normal if they
showed no stenosis or only slight wall irregularities on visual assessment.
Patients with a final non-cardiac diagnosis for the chest pain were excluded.
RESULTS: A total of 558 patients were included. Of these, 151 (27%) showed normal
or near-normal coronary arteries on visual assessment. This group of patients
were significantly more often female (p < 0.001), younger (p < 0.001) and
non-diabetic (p = 0.002). Forty percent of hospitalised patients who had normal
or near-normal coronary arteries at coronary angiography showed an elevated
troponin. CONCLUSION: In routine cardiological practice, around 1 out of
4 patients with suspected cardiac chest pain undergoing invasive angiography had
normal or near-normal coronary arteries. We suggest that premenopausal women with
suspected cardiac chest pain could be considered for non-invasive coronary
imaging as a first step in clinical practice.