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10.1007/978-1-4939-3801-8_6

http://scihub22266oqcxt.onion/10.1007/978-1-4939-3801-8_6
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C5435480!5435480!27581015
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suck abstract from ncbi

pmid27581015      Methods+Mol+Biol 2016 ; 1458 (ä): 71-85
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  • Measuring Vascular Permeability In Vivo #MMPMID27581015
  • Meijer EF; Baish JW; Padera TP; Fukumura D
  • Methods Mol Biol 2016[]; 1458 (ä): 71-85 PMID27581015show ga
  • Over the past decades, in vivo vascular permeability measurements have provided significant insight into vascular functions in physiological and pathophysiological conditions such as the response to pro- and anti-angiogenic signaling, abnormality of tumor vasculature and its normalization, and delivery and efficacy of therapeutic agents. Different approaches for vascular permeability measurements have been established. Here, we describe and discuss a conventional 2D imaging method to measure vascular permeability, which was originally documented by Gerlowski and Jain in 1986 (Microvasc Res 31:288?305, 1986) and further developed by Yuan et al. in the early 1990s (Microvasc Res 45:269?289, 1993; Cancer Res 54:352?3356, 1994), and our recently developed 3D imaging method, which advances the approach originally described by Brown et al. in 2001 (Nat Med 7:864?868, 2001).
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