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10.1038/s41598-017-02030-6 http://scihub22266oqcxt.onion/10.1038/s41598-017-02030-6 C5434027!5434027 !28512320     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28512320 &cmd=llinks): Failed to open stream: HTTP request failed! 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Hyponatremia upon presentation to the emergency department - the need for urgent neuroimaging studies |pdf=|usr=}}{{28512320 }} gab.com Text Hyponatremia upon presentation to the emergency department - the need for urgent neuroimaging studies JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=28512320 #FOAvip This study aims to evaluate the necessity of urgent neuroimaging for emergency admissions exhibiting symptomatology of profound hyponatremia. We retrospectively analyzed the medical records of all patients admitted to the emergency room of the University Hospital Münster from 2010 to 2014 with a serum sodium value < 125?mmol/L. From 52918 emergency admissions, 261 patients with profound hyponatremia were identified, of whom 140 (54%) had neurological symptoms. Unspecific weakness and confusion were the most prevalent of these symptoms (59%). Focal neurological signs [FNS] were present in 31% of cases and neuroimaging was performed in 68% (95/140) of symptomatic patients. Multiple logistic regression analysis identified FNS, seizures, altered consciousness and age as independent predictors for conducting neuroimaging (all p?<?0.05). Significant pathological findings consistent with acute symptomatology were evident in 17 cases, all of whom had FNS. Recursive partitioning analyses confirmed FNS as the best predictor of neuroimaging pathology (p?<?0.001). Absence of FNS had a negative predictive value of 100% [95% confidence interval: 93-100%] for excluding neuroimaging pathology. In conclusion, emergency patients with profound hyponatremia frequently show nonspecific-neurological symptoms and may undergo neuroimaging unnecessarily. The lack of FNS may serve as a valuable criterion for withholding neuroimaging until hyponatremia has been corrected. Twit Text FOAVip Hyponatremia upon presentation to the emergency department - the need for urgent neuroimaging studies ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=28512320 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28512320 #FOAvip English Wikipedia <ref>{{Cite pmid|28512320 }}</ref> Hyponatremia upon presentation to the emergency department - the need for urgent neuroimaging studies #MMPMID28512320 Bokemeyer A ; Dziewas R ; Wiendl H ; Schwindt W ; Bicsán P ; Kümpers P ; Pavenstädt H Sci Rep 2017[May]; 7 (1 ): 1953 PMID28512320 show ga This study aims to evaluate the necessity of urgent neuroimaging for emergency admissions exhibiting symptomatology of profound hyponatremia. We retrospectively analyzed the medical records of all patients admitted to the emergency room of the University Hospital Münster from 2010 to 2014 with a serum sodium value < 125?mmol/L. From 52918 emergency admissions, 261 patients with profound hyponatremia were identified, of whom 140 (54%) had neurological symptoms. Unspecific weakness and confusion were the most prevalent of these symptoms (59%). Focal neurological signs [FNS] were present in 31% of cases and neuroimaging was performed in 68% (95/140) of symptomatic patients. Multiple logistic regression analysis identified FNS, seizures, altered consciousness and age as independent predictors for conducting neuroimaging (all p? |*Emergency Medical Services [MESH] |*Emergency Service, Hospital [MESH] |Aged [MESH] |Biomarkers [MESH] |Disease Management [MESH] |Female [MESH] |Humans [MESH] |Hyponatremia/*diagnosis/etiology/therapy [MESH] |Male [MESH] |Middle Aged [MESH] |Multimodal Imaging/methods [MESH] |Neuroimaging/methods [MESH] |Prognosis [MESH] |Symptom Assessment [MESH]Hyponatremia upon presentation to the emergency department - the need (epmc).pdf DeepDyve Pubget Overpricing