Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28506221
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 BMC+Nephrol
2017 ; 18
(1
): 160
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
The association between urbanization and reduced renal function: findings from
the China Health and Nutrition Survey
#MMPMID28506221
Inoue Y
; Howard AG
; Thompson AL
; Mendez MA
; Herring AH
; Gordon-Larsen P
BMC Nephrol
2017[May]; 18
(1
): 160
PMID28506221
show ga
BACKGROUND: While chronic kidney disease (CKD) is a growing public health concern
in low- and middle-income countries, such as China, few studies have investigated
the association between urbanization and the occurrence of CKD in those
countries. METHODS: We investigated the association between urbanization and
estimated glomerular filtration rate (eGFR), an important CKD risk marker. Data
came from the China Health and Nutrition Survey wave 2009, in which we collected
fasting serum, individual and household data along with community level
urbanization data, which was used to derive a study-specific urbanization
measure, in 218 communities across nine provinces. A total of 3644 men and 4154
women participants aged 18 years or older were included in the analysis. Reduced
renal function was defined as eGFR of less than 60 mL/min/1.73 m(2) measured
using serum creatinine concentration (mg/dL). RESULTS: After adjusting for
socio-demographic (e.g., age, education and household income), a sex-stratified
multilevel logistic model revealed that living in a more urbanized community was
associated with higher odds of reduced eGFR (odds ratio [OR] = 1.38 per
one-standard deviation [SD] increase in the CHNS specific urbanization index, 95%
confidence interval [CI] = 1.11-1.73 for men; OR = 1.35, 95% CI = 1.11-1.62 for
women). After adjusting for behavioral variables (i.e., alcohol consumption,
smoking, physical activity and diet), as well as obesity and cardiometabolic risk
factors, the association was attenuated in men (OR = 1.25, 95% CI = 0.98-1.59),
but remained statistically significant in women (OR = 1.24, 95% CI = 1.01-1.52).
CONCLUSION: Our findings suggest that living in an urban environment is linked
with higher odds of reduced renal function independently of behavioral and
cardiometabolic risk factors, which have been shown to increase along with
urbanization.
|*Glomerular Filtration Rate
[MESH]
|*Urbanization
[MESH]
|Age Distribution
[MESH]
|Aged
[MESH]
|China/epidemiology
[MESH]
|Educational Status
[MESH]
|Female
[MESH]
|Health Status
[MESH]
|Health Surveys/*statistics & numerical data
[MESH]
|Humans
[MESH]
|Incidence
[MESH]
|Kidney Function Tests/*statistics & numerical data
[MESH]
|Longitudinal Studies
[MESH]
|Male
[MESH]
|Middle Aged
[MESH]
|Nutrition Surveys/*statistics & numerical data
[MESH]