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10.1016/j.cell.2017.02.007 http://scihub22266oqcxt.onion/10.1016/j.cell.2017.02.007 C5432200!5432200!28340338     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell 2017 ; 169 (1): 13-23 Nephropedia Template TP {{tp|p=28340338|t=2017. A phase separation model predicts key features of transcriptional control |pdf=|usr=}}{{28340338}} gab.com Text A phase separation model predicts key features of transcriptional control JO: Cell http://www.kidney.de/pget.php?&tw=1&pmid=28340338 #FOAvip Super-enhancers are large clusters of enhancers that control transcription of genes with prominent roles in cell-type specific processes in healthy and diseased states. A model that explains the spectrum of observations regarding super-enhancer formation, function and dissolution is lacking. Phase-separated multi-molecular assemblies provide an essential regulatory mechanism to compartmentalize biochemical reactions within cells. We propose that a phase separation model explains features of transcriptional control, including the formation of super-enhancers, the sensitivity of super-enhancers to perturbation, and their transcriptional bursting patterns. This model provides a conceptual framework to further explore principles of gene control in mammals. Twit Text FOAVip A phase separation model predicts key features of transcriptional control ????Cell http://www.kidney.de/pget.php?&tw=1&pmid=28340338 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28340338 #FOAvip English Wikipedia <ref>{{Cite pmid|28340338}}</ref> A phase separation model predicts key features of transcriptional control #MMPMID28340338 Hnisz D; Shrinivas K; Young RA; Chakraborty AK; Sharp PA Cell 2017[Mar]; 169 (1): 13-23 PMID28340338show ga Super-enhancers are large clusters of enhancers that control transcription of genes with prominent roles in cell-type specific processes in healthy and diseased states. A model that explains the spectrum of observations regarding super-enhancer formation, function and dissolution is lacking. Phase-separated multi-molecular assemblies provide an essential regulatory mechanism to compartmentalize biochemical reactions within cells. We propose that a phase separation model explains features of transcriptional control, including the formation of super-enhancers, the sensitivity of super-enhancers to perturbation, and their transcriptional bursting patterns. This model provides a conceptual framework to further explore principles of gene control in mammals. äA phase separation model predicts key features of transcriptional cont(epmc).pdf DeepDyve Pubget Overpricing