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10.1038/s41598-017-01229-x http://scihub22266oqcxt.onion/10.1038/s41598-017-01229-x C5430737!5430737!28450732     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2017 ; 7 (ä): ä Nephropedia Template TP {{tp|p=28450732|t=2017. Ultra-weak photon emission as a dynamic tool for monitoring oxidative stress metabolism |pdf=|usr=}}{{28450732}} gab.com Text Ultra-weak photon emission as a dynamic tool for monitoring oxidative stress metabolism JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=28450732 #FOAvip In recent years, excessive oxidative metabolism has been reported as a critical determinant of pathogenicity in many diseases. The advent of a simple tool that can provide a physiological readout of oxidative stress would be a major step towards monitoring this dynamic process in biological systems, while also improving our understanding of this process. Ultra-weak photon emission (UPE) has been proposed as a potential tool for measuring oxidative processes due to the association between UPE and reactive oxygen species. Here, we used HL-60 cells as an in vitro model to test the potential of using UPE as readout for dynamically monitoring oxidative stress after inducing respiratory burst. In addition, to probe for possible changes in oxidative metabolism, we performed targeted metabolomics on cell extracts and culture medium. Lastly, we tested the effects of treating cells with the NADPH oxidase inhibitor diphenyleneiodonium chloride (DPI). Our results show that UPE can be used as readout for measuring oxidative stress metabolism and related processes. Twit Text FOAVip Ultra-weak photon emission as a dynamic tool for monitoring oxidative stress metabolism ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=28450732 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28450732 #FOAvip English Wikipedia <ref>{{Cite pmid|28450732}}</ref> Ultra-weak photon emission as a dynamic tool for monitoring oxidative stress metabolism #MMPMID28450732 Burgos RCR; Schoeman JC; Winden LJv; ?ervinková K; Ramautar R; Van Wijk EPA; Cifra M; Berger R; Hankemeier T; Greef Jvan d Sci Rep 2017[]; 7 (ä): ä PMID28450732show ga In recent years, excessive oxidative metabolism has been reported as a critical determinant of pathogenicity in many diseases. The advent of a simple tool that can provide a physiological readout of oxidative stress would be a major step towards monitoring this dynamic process in biological systems, while also improving our understanding of this process. Ultra-weak photon emission (UPE) has been proposed as a potential tool for measuring oxidative processes due to the association between UPE and reactive oxygen species. Here, we used HL-60 cells as an in vitro model to test the potential of using UPE as readout for dynamically monitoring oxidative stress after inducing respiratory burst. In addition, to probe for possible changes in oxidative metabolism, we performed targeted metabolomics on cell extracts and culture medium. Lastly, we tested the effects of treating cells with the NADPH oxidase inhibitor diphenyleneiodonium chloride (DPI). Our results show that UPE can be used as readout for measuring oxidative stress metabolism and related processes. äUltra-weak photon emission as a dynamic tool for monitoring oxidative (epmc).pdf DeepDyve Pubget Overpricing