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10.1113/JP272781

http://scihub22266oqcxt.onion/10.1113/JP272781
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C5430224!5430224!28303572
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suck abstract from ncbi

pmid28303572      J+Physiol 2017 ; 595 (10): 3041-51
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  • Intracellular calcium release channels: an update #MMPMID28303572
  • Santulli G; Nakashima R; Yuan Q; Marks AR
  • J Physiol 2017[May]; 595 (10): 3041-51 PMID28303572show ga
  • Ryanodine receptors (RyRs) and inositol 1,4,5?trisphosphate receptors (IP3Rs) are calcium (Ca2+) release channels on the endo/sarcoplasmic reticulum (ER/SR). Here we summarize the latest advances in the field, describing the recently discovered mechanistic roles of intracellular Ca2+ release channels in the regulation of mitochondrial fitness and endothelial function, providing novel therapeutic options for the treatment of heart failure, hypertension, and diabetes mellitus.
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