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10.1017/S0950268817000528 http://scihub22266oqcxt.onion/10.1017/S0950268817000528 C5426289!5426289!28325163     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Epidemiol+Infect 2017 ; 145 (8): 1617-23 Nephropedia Template TP {{tp|p=28325163|t=2017. Proton pump inhibitors as a risk factor for norovirus infection |pdf=|usr=}}{{28325163}} gab.com Text Proton pump inhibitors as a risk factor for norovirus infection JO: Epidemiol Infect http://www.kidney.de/pget.php?&tw=1&pmid=28325163 #FOAvip Norovirus causes viral gastroenteritis, which is a major problem in health care. The disease causes death in elderly and seriously ill patients, and results in significant health costs each year. Proton pump inhibitors (PPIs) reduce gastric acidity, which is an important protection against microorganisms. We hypothesised that treatment with PPIs increases the risk of contracting norovirus infection. This has not previously been studied. The study was a retrospective case?control study, in which 192 hospitalised patients positive for norovirus in Örebro County, Sweden, were identified as cases. For each case, a hospitalised patient who did not have the infection was selected as a control, and matched with respect to ward, gender, admission date and age. Details of exposure, i.e. treatment with PPIs, were retrieved from the patient records. Odds ratio (OR) with confidence intervals (CIs) and P-values were calculated using McNemar's test. There was a significantly increased risk of norovirus infection in patients treated with PPIs compared with patients without PPI treatment (OR 1·73, 95% CI 1·07?2·81; P = 0·02). PPIs appear to be a risk factor for norovirus infection, and our results motivate future studies to further examine this association. Twit Text FOAVip Proton pump inhibitors as a risk factor for norovirus infection ????Epidemiol Infect http://www.kidney.de/pget.php?&tw=1&pmid=28325163 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28325163 #FOAvip English Wikipedia <ref>{{Cite pmid|28325163}}</ref> Proton pump inhibitors as a risk factor for norovirus infection #MMPMID28325163 PRAG C; PRAG M; FREDLUND H Epidemiol Infect 2017[Jun]; 145 (8): 1617-23 PMID28325163show ga Norovirus causes viral gastroenteritis, which is a major problem in health care. The disease causes death in elderly and seriously ill patients, and results in significant health costs each year. Proton pump inhibitors (PPIs) reduce gastric acidity, which is an important protection against microorganisms. We hypothesised that treatment with PPIs increases the risk of contracting norovirus infection. This has not previously been studied. The study was a retrospective case?control study, in which 192 hospitalised patients positive for norovirus in Örebro County, Sweden, were identified as cases. For each case, a hospitalised patient who did not have the infection was selected as a control, and matched with respect to ward, gender, admission date and age. Details of exposure, i.e. treatment with PPIs, were retrieved from the patient records. Odds ratio (OR) with confidence intervals (CIs) and P-values were calculated using McNemar's test. There was a significantly increased risk of norovirus infection in patients treated with PPIs compared with patients without PPI treatment (OR 1·73, 95% CI 1·07?2·81; P = 0·02). PPIs appear to be a risk factor for norovirus infection, and our results motivate future studies to further examine this association. äProton pump inhibitors as a risk factor for norovirus infection (epmc).pdf DeepDyve Pubget Overpricing