Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1016/j.neubiorev.2017.01.045 http://scihub22266oqcxt.onion/10.1016/j.neubiorev.2017.01.045 C5425954!5425954!28163193     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Neurosci+Biobehav+Rev 2017 ; 75 (ä): 378-92 Nephropedia Template TP {{tp|p=28163193|t=2017. The Neuropathological Signature of Bulbar-onset ALS: A Systematic Review |pdf=|usr=}}{{28163193}} gab.com Text The Neuropathological Signature of Bulbar-onset ALS: A Systematic Review JO: Neurosci Biobehav Rev http://www.kidney.de/pget.php?&tw=1&pmid=28163193 #FOAvip ALS is a multisystem disorder affecting cognitive and motor functions. Bulbar-onset ALS (bALS) may be preferentially associated with language/cognitive impairments, compared with spinal-onset ALS (sALS), stemming from a potentially unique neuropathology. The objective of this systematic review was to compare neuropathology reported for bALS and sALS subtypes in studies of cadaveric brains. Using Cochrane guidelines, we reviewed articles in MEDLINE, Embase, and PsycINFO databases using standardized search terms for ALS and neuropathology, from inception until July 16th 2016. 17 studies were accepted. In summary, both subtypes presented with involvement in motor and frontotemporal cortices, deep cortical structures, and cerebellum, characterized by neuronal loss, spongiosis, myelin pallor, and ubiquitin+ and TDP43+ inclusion bodies. Changes in Broca and Wernicke areas, regions associated with speech and language processing, were noted exclusively in bALS. Further, some bALS cases presented with atypical pathology, neurofibrillary tangles and basophilic inclusions, which were not found in any sALS cases. Given the few studies, all with methodological biases, further work is required to better understand neuropathology of ALS subtypes. Twit Text FOAVip The Neuropathological Signature of Bulbar-onset ALS: A Systematic Review ????Neurosci Biobehav Rev http://www.kidney.de/pget.php?&tw=1&pmid=28163193 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28163193 #FOAvip English Wikipedia <ref>{{Cite pmid|28163193}}</ref> The Neuropathological Signature of Bulbar-onset ALS: A Systematic Review #MMPMID28163193 Shellikeri S; Karthikeyan V; Martino R; Black S; Zinman L; Keith J; Yunusova Y Neurosci Biobehav Rev 2017[Apr]; 75 (ä): 378-92 PMID28163193show ga ALS is a multisystem disorder affecting cognitive and motor functions. Bulbar-onset ALS (bALS) may be preferentially associated with language/cognitive impairments, compared with spinal-onset ALS (sALS), stemming from a potentially unique neuropathology. The objective of this systematic review was to compare neuropathology reported for bALS and sALS subtypes in studies of cadaveric brains. Using Cochrane guidelines, we reviewed articles in MEDLINE, Embase, and PsycINFO databases using standardized search terms for ALS and neuropathology, from inception until July 16th 2016. 17 studies were accepted. In summary, both subtypes presented with involvement in motor and frontotemporal cortices, deep cortical structures, and cerebellum, characterized by neuronal loss, spongiosis, myelin pallor, and ubiquitin+ and TDP43+ inclusion bodies. Changes in Broca and Wernicke areas, regions associated with speech and language processing, were noted exclusively in bALS. Further, some bALS cases presented with atypical pathology, neurofibrillary tangles and basophilic inclusions, which were not found in any sALS cases. Given the few studies, all with methodological biases, further work is required to better understand neuropathology of ALS subtypes. äThe Neuropathological Signature of Bulbar-onset ALS: A Systematic Revi(epmc).pdf DeepDyve Pubget Overpricing