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10.2174/1573395510666141105234917 http://scihub22266oqcxt.onion/10.2174/1573395510666141105234917 C5425648/?report=reader!5425648!C5425648     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Curr+Med+Chem 2015 ; 11 (1): 43-54 Nephropedia Template TP {{tp|p=C5425648|t=2015. Interrelated Roles for the Aryl Hydrocarbon Receptor and Hypoxia Inducible Factor-1? in the Immune Response to Infection |pdf=|usr=}}{{C5425648}} gab.com Text Interrelated Roles for the Aryl Hydrocarbon Receptor and Hypoxia Inducible Factor-1 in the Immune Response to Infection JO: Curr Med Chem http://www.kidney.de/pget.php?&tw=1&pmid=C5425648 #FOAvip Cells of the immune system utilize multiple mechanisms to respond to environmental signals and recent studies have demonstrated roles for two closely related proteins, the aryl hydrocarbon receptor (AHR) and hypoxia inducible factor-1? (HIF1?), in these processes. The AHR is a transcription factor that is activated by diverse ligands found in the diet and environmental pollution as well as by microbial and host-derived products. In contrast, HIF1? is a transcription factor that is active under low oxygen conditions and mediates cellular responses to hypoxia. These evolutionarily conserved proteins have roles in the interrelated processes of metabolism, tumorigenesis, and vascular development. Additionally, the AHR and HIF1? have multiple effects on innate and adaptive immunity. This article provides an overview of the biology of these transcription factors and reviews the effects of AHR and HIF1? signaling on immunity to infection. There are many parallels between these two pathways and their functions highlight the importance of AHR and HIF1? activity particularly at barrier surfaces in coordinating responses to pathogens. Twit Text FOAVip Interrelated Roles for the Aryl Hydrocarbon Receptor and Hypoxia Inducible Factor-1 in the Immune Response to Infection ????Curr Med Chem http://www.kidney.de/pget.php?&tw=1&pmid=C5425648 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=C5425648 #FOAvip English Wikipedia <ref>{{Cite pmid|C5425648}}</ref> Interrelated Roles for the Aryl Hydrocarbon Receptor and Hypoxia Inducible Factor-1? in the Immune Response to Infection #MMPMIDC5425648 Wagage S; Hunter CA Curr Med Chem 2015[Apr]; 11 (1): 43-54 PMIDC5425648show ga Cells of the immune system utilize multiple mechanisms to respond to environmental signals and recent studies have demonstrated roles for two closely related proteins, the aryl hydrocarbon receptor (AHR) and hypoxia inducible factor-1? (HIF1?), in these processes. The AHR is a transcription factor that is activated by diverse ligands found in the diet and environmental pollution as well as by microbial and host-derived products. In contrast, HIF1? is a transcription factor that is active under low oxygen conditions and mediates cellular responses to hypoxia. These evolutionarily conserved proteins have roles in the interrelated processes of metabolism, tumorigenesis, and vascular development. Additionally, the AHR and HIF1? have multiple effects on innate and adaptive immunity. This article provides an overview of the biology of these transcription factors and reviews the effects of AHR and HIF1? signaling on immunity to infection. There are many parallels between these two pathways and their functions highlight the importance of AHR and HIF1? activity particularly at barrier surfaces in coordinating responses to pathogens. äInterrelated Roles for the Aryl Hydrocarbon Receptor and Hypoxia Induc(epmc).pdf DeepDyve Pubget Overpricing