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10.5527/wjn.v6.i3.111 http://scihub22266oqcxt.onion/10.5527/wjn.v6.i3.111 C5424432!5424432!28540200     free     free     free Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       World+J+Nephrol 2017 ; 6 (3): 111-8 Nephropedia Template TP {{tp|p=28540200|t=2017. Targeting cannabinoid signaling for peritoneal dialysis-induced oxidative stress and fibrosis |pdf=|usr=}}{{28540200}} gab.com Text Targeting cannabinoid signaling for peritoneal dialysis-induced oxidative stress and fibrosis JO: World J Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=28540200 #FOAvip Long-term exposure to bioincompatible peritoneal dialysis (PD) solutions frequently results in peritoneal fibrosis and ultrafiltration failure, which limits the life-long use of and leads to the cessation of PD therapy. Therefore, it is important to elucidate the pathogenesis of peritoneal fibrosis in order to design therapeutic strategies to prevent its occurrence. Peritoneal fibrosis is associated with a chronic inflammatory status as well as an elevated oxidative stress (OS) status. Beyond uremia per se, OS also results from chronic exposure to high glucose load, glucose degradation products, advanced glycation end products, and hypertonic stress. Therapy targeting the cannabinoid (CB) signaling pathway has been reported in several chronic inflammatory diseases with elevated OS. We recently reported that the intra-peritoneal administration of CB receptor ligands, including CB1 receptor antagonists and CB2 receptor agonists, ameliorated dialysis-related peritoneal fibrosis. As targeting the CB signaling pathway has been reported to be beneficial in attenuating the processes of several chronic inflammatory diseases, we reviewed the interaction among the cannabinoid system, inflammation, and OS, through which clinicians ultimately aim to prolong the peritoneal survival of PD patients. Twit Text FOAVip Targeting cannabinoid signaling for peritoneal dialysis-induced oxidative stress and fibrosis ????World J Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=28540200 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28540200 #FOAvip English Wikipedia <ref>{{Cite pmid|28540200}}</ref> Targeting cannabinoid signaling for peritoneal dialysis-induced oxidative stress and fibrosis #MMPMID28540200 Yang CY; Chau YP; Chen A; Lee OKS; Tarng DC; Yang AH World J Nephrol 2017[May]; 6 (3): 111-8 PMID28540200show ga Long-term exposure to bioincompatible peritoneal dialysis (PD) solutions frequently results in peritoneal fibrosis and ultrafiltration failure, which limits the life-long use of and leads to the cessation of PD therapy. Therefore, it is important to elucidate the pathogenesis of peritoneal fibrosis in order to design therapeutic strategies to prevent its occurrence. Peritoneal fibrosis is associated with a chronic inflammatory status as well as an elevated oxidative stress (OS) status. Beyond uremia per se, OS also results from chronic exposure to high glucose load, glucose degradation products, advanced glycation end products, and hypertonic stress. Therapy targeting the cannabinoid (CB) signaling pathway has been reported in several chronic inflammatory diseases with elevated OS. We recently reported that the intra-peritoneal administration of CB receptor ligands, including CB1 receptor antagonists and CB2 receptor agonists, ameliorated dialysis-related peritoneal fibrosis. As targeting the CB signaling pathway has been reported to be beneficial in attenuating the processes of several chronic inflammatory diseases, we reviewed the interaction among the cannabinoid system, inflammation, and OS, through which clinicians ultimately aim to prolong the peritoneal survival of PD patients. äTargeting cannabinoid signaling for peritoneal dialysis-induced oxidat(epmc).pdf DeepDyve Pubget Overpricing