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2017 ; 11
(1
): 130
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English Wikipedia
Langerhans cell histiocytosis of the maxillae in a child treated only with
chemotherapy: a case report
#MMPMID28482919
Cazzolla AP
; Troiano G
; Zhurakivska K
; Maiorano E
; Favia G
; Lacaita MG
; Marzo G
; Dicuonzo F
; Andresciani S
; Muzio LL
J Med Case Rep
2017[May]; 11
(1
): 130
PMID28482919
show ga
BACKGROUND: Langerhans cell histiocytosis is a sporadic disease caused by an
uncontrolled pathogenic clonal proliferation of dendritic cells that have
Langerhans cell characteristics. New treatment protocols provided by the
HISTSOC-LCH-III (NCT00276757) trial show an improvement in the survival of
children with langerhans cell histiocytosis. CASE PRESENTATION: We report a case
of Langerhans cell histiocytosis, which presented as an osteolytic lesion of the
left pre-maxillae enclosing the deciduous incisor and canine in a 7-month-old
white Italian boy. He was treated with chemotherapy. He achieved complete
remission after 7 months and after 24 months no signs of recurrence were
observed. CONCLUSIONS: As a result of this treatment, anesthetic sequelae and
loss of teeth were avoided; in addition, we prevented a loss of the vertical
dimension of occlusion.