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10.1073/pnas.1620008114 http://scihub22266oqcxt.onion/10.1073/pnas.1620008114 C5422765!5422765!28373558     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28373558&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Proc+Natl+Acad+Sci+U+S+A 2017 ; 114 (18): 4805-10 Nephropedia Template TP {{tp|p=28373558|t=2017. Direct visualization of the arterial wall water permeability barrier using CARS microscopy |pdf=|usr=}}{{28373558}} gab.com Text Direct visualization of the arterial wall water permeability barrier using CARS microscopy JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=28373558 #FOAvip Low water permeability is critical to the pressurized blood conduit function of the artery. Arterial wall permeability is altered in diseases including diabetes and atherosclerosis, in acute shock, and with the aging process. Here we directly map the water permeability and the associated pressure profile across intact pressurized arteries with coherent anti-Stokes Raman scattering microscopy and D2O tracer experiments. We identify the endothelial basolateral membrane as the major barrier to water permeation. The advantageously positioned water barrier permits the direct transfer of arterial pressure to subendothelial elastic macromolecules. The mechanically sensitive endothelial cell is thus protected from static or pulsed-pressure?induced deformation. Disruption of this pressure transmission could contribute to endothelial dysfunction in various disease states. Twit Text FOAVip Direct visualization of the arterial wall water permeability barrier using CARS microscopy ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=28373558 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28373558 #FOAvip English Wikipedia <ref>{{Cite pmid|28373558}}</ref> Direct visualization of the arterial wall water permeability barrier using CARS microscopy #MMPMID28373558 Lucotte BM; Powell C; Knutson JR; Combs CA; Malide D; Yu ZX; Knepper M; Patel KD; Pielach A; Johnson E; Borysova L; Dora KA; Balaban RS Proc Natl Acad Sci U S A 2017[May]; 114 (18): 4805-10 PMID28373558show ga Low water permeability is critical to the pressurized blood conduit function of the artery. Arterial wall permeability is altered in diseases including diabetes and atherosclerosis, in acute shock, and with the aging process. Here we directly map the water permeability and the associated pressure profile across intact pressurized arteries with coherent anti-Stokes Raman scattering microscopy and D2O tracer experiments. We identify the endothelial basolateral membrane as the major barrier to water permeation. The advantageously positioned water barrier permits the direct transfer of arterial pressure to subendothelial elastic macromolecules. The mechanically sensitive endothelial cell is thus protected from static or pulsed-pressure?induced deformation. Disruption of this pressure transmission could contribute to endothelial dysfunction in various disease states. äDirect visualization of the arterial wall water permeability barrier u(epmc).pdf DeepDyve Pubget Overpricing