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2017 ; 6
(2
): 295-304
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
The impact and management of sexual dysfunction secondary to pharmacological
therapy of benign prostatic hyperplasia
#MMPMID28540239
Gandhi J
; Weissbart SJ
; Smith NL
; Kaplan SA
; Dagur G
; Zumbo A
; Joshi G
; Khan SA
Transl Androl Urol
2017[Apr]; 6
(2
): 295-304
PMID28540239
show ga
Benign prostatic hyperplasia (BPH) is one of the most common genitourinary
complications in men over 50 years of age and typically presents with lower
urinary tract symptoms (LUTS). Classes of medications include ?1-adrenoceptor
blockers, 5?-reductase inhibitors, and phosphodiesterase 5 inhibitors. Today,
?1-adrenoceptor blockers and 5?-reductase inhibitors are often combined to give a
synergistic effect. A review of the current literature identified several adverse
sexual side effects, including erectile dysfunction (ED), decreased libido,
orgasmic disorders, and ejaculatory disorders. We believe it is important to know
the extent of these side effects, as the clinician and patient will need to
decide the cost of improved voiding symptoms. The chief adverse effect is
ejaculatory disorders, including the absence of ejaculation. Clinical
consideration for BPH should include the elements of male sexual function,
patients' age, and the characteristics and comprehensive effects of each group of
drugs. Methodological bias in clinical studies, such as the subjective evaluation
of the sexual side effect, makes it difficult to determine the ideal drug for
treatment.