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10.3389/fimmu.2017.00515 http://scihub22266oqcxt.onion/10.3389/fimmu.2017.00515 C5421149!5421149!28533777     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Immunol 2017 ; 8 (ä): ä Nephropedia Template TP {{tp|p=28533777|t=2017. Alternative Anaphylactic Routes: The Potential Role of Macrophages |pdf=|usr=}}{{28533777}} gab.com Text Alternative Anaphylactic Routes: The Potential Role of Macrophages JO: Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=28533777 #FOAvip Anaphylaxis is an acute, life-threatening, multisystem syndrome resulting from the sudden release of mediators from effector cells. There are two potential pathways for anaphylaxis. The first one, IgE-dependent anaphylaxis, is induced by antigen (Ag) cross-linking of Ag-specific IgE bound to the high-affinity IgE receptor (Fc?RI) on mast cells and basophils. The second one, IgG-dependent anaphylaxis is induced by Ag cross-linking of Ag-specific IgG bound to IgG receptors (Fc?RI, Fc?RIIA, Fc?RIIB, Fc?RIIC, and Fc?RIIIA) on macrophages, neutrophils, and basophils. Macrophages exhibit a huge functional plasticity and are capable of exerting their scavenging, bactericidal, and regulatory functions under a wide variety of tissue conditions. Herein, we will review their potential role in the triggering and development of anaphylaxis. Thereby, macrophages, among other immune cells, play a role in both anaphylactic pathways (1) by responding to anaphylactic mediators secreted by mast cells after specific IgE cross-linking or (2) by acting as effector cells in the anaphylactic response mediated by IgG. In this review, we will go over the cellular and molecular mechanisms that take place in the above-mentioned anaphylactic pathways and will discuss the clinical implications in human allergic reactions. Twit Text FOAVip Alternative Anaphylactic Routes: The Potential Role of Macrophages ????Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=28533777 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28533777 #FOAvip English Wikipedia <ref>{{Cite pmid|28533777}}</ref> Alternative Anaphylactic Routes: The Potential Role of Macrophages #MMPMID28533777 Escribese MM; Rosace D; Chivato T; Fernández TD; Corbí AL; Barber D Front Immunol 2017[]; 8 (ä): ä PMID28533777show ga Anaphylaxis is an acute, life-threatening, multisystem syndrome resulting from the sudden release of mediators from effector cells. There are two potential pathways for anaphylaxis. The first one, IgE-dependent anaphylaxis, is induced by antigen (Ag) cross-linking of Ag-specific IgE bound to the high-affinity IgE receptor (Fc?RI) on mast cells and basophils. The second one, IgG-dependent anaphylaxis is induced by Ag cross-linking of Ag-specific IgG bound to IgG receptors (Fc?RI, Fc?RIIA, Fc?RIIB, Fc?RIIC, and Fc?RIIIA) on macrophages, neutrophils, and basophils. Macrophages exhibit a huge functional plasticity and are capable of exerting their scavenging, bactericidal, and regulatory functions under a wide variety of tissue conditions. Herein, we will review their potential role in the triggering and development of anaphylaxis. Thereby, macrophages, among other immune cells, play a role in both anaphylactic pathways (1) by responding to anaphylactic mediators secreted by mast cells after specific IgE cross-linking or (2) by acting as effector cells in the anaphylactic response mediated by IgG. In this review, we will go over the cellular and molecular mechanisms that take place in the above-mentioned anaphylactic pathways and will discuss the clinical implications in human allergic reactions. äAlternative Anaphylactic Routes: The Potential Role of Macrophages (epmc).pdf DeepDyve Pubget Overpricing