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10.1016/j.ijwd.2016.09.003 http://scihub22266oqcxt.onion/10.1016/j.ijwd.2016.09.003 C5419024!5419024!28492030     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Womens+Dermatol 2016 ; 2 (4): 151-3 Nephropedia Template TP {{tp|p=28492030|t=2016. Managing the dose escalation of biologics in an era of cost containment: the need for a rational strategy??? |pdf=|usr=}}{{28492030}} gab.com Text Managing the dose escalation of biologics in an era of cost containment: the need for a rational strategy JO: Int J Womens Dermatol http://www.kidney.de/pget.php?&tw=1&pmid=28492030 #FOAvip Although biologic medications have demonstrated great efficacy for the treatment of psoriasis, a subset of patients fails to respond and others lose response later in the course. In treating a patient who has failed to respond to biologic therapy, clinicians must decide between dose escalation, switching biologics, and adding or switching to a non-biologic systemic drug or phototherapy. Although dose escalation is perhaps the simplest strategy and generally well-tolerated, it confers a tremendous cost burden because doubling the dosage is likely to double the wholesale price. We call for the development of rational strategies for the pricing of dose escalation in order to minimize this phenomenon. We also call for increased transparency surrounding negotiated pricing to ensure that all patients have access to the most effective, affordable treatment options available. Twit Text FOAVip Managing the dose escalation of biologics in an era of cost containment: the need for a rational strategy ????Int J Womens Dermatol http://www.kidney.de/pget.php?&tw=1&pmid=28492030 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28492030 #FOAvip English Wikipedia <ref>{{Cite pmid|28492030}}</ref> Managing the dose escalation of biologics in an era of cost containment: the need for a rational strategy??? #MMPMID28492030 Shahwan K; Kimball A Int J Womens Dermatol 2016[Dec]; 2 (4): 151-3 PMID28492030show ga Although biologic medications have demonstrated great efficacy for the treatment of psoriasis, a subset of patients fails to respond and others lose response later in the course. In treating a patient who has failed to respond to biologic therapy, clinicians must decide between dose escalation, switching biologics, and adding or switching to a non-biologic systemic drug or phototherapy. Although dose escalation is perhaps the simplest strategy and generally well-tolerated, it confers a tremendous cost burden because doubling the dosage is likely to double the wholesale price. We call for the development of rational strategies for the pricing of dose escalation in order to minimize this phenomenon. We also call for increased transparency surrounding negotiated pricing to ensure that all patients have access to the most effective, affordable treatment options available. äManaging the dose escalation of biologics in an era of cost containmen(epmc).pdf DeepDyve Pubget Overpricing