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2016 ; 3
(ä): 2329048X16632140
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Encephalopathy and Axonal Neuropathy Associated With Mycoplasma Pneumoniae
Infection: Response to Intravenous Immunoglobulin Therapy
#MMPMID28503607
Saker A
; Athman S
; Aldosari M
; Frayha H
Child Neurol Open
2016[Jan]; 3
(ä): 2329048X16632140
PMID28503607
show ga
Mycoplasma pneumoniae infection frequently presents as a self-limited process,
however, severe cases and even fatalities have been reported. The authors present
a case of Mycoplasma pneumoniae infection associated with both encephalopathy and
peripheral neuropathy that responded to intravenous immunoglobulin therapy. To
our knowledge, this is the first documented case of Mycoplasma pneumoniae related
to encephalitis and peripheral axonal neuropathy. To date, there is insufficient
data on the effect of intravenous immunoglobulin on the course of
mycoplasma-associated central nervous system/peripheral nervous system disease.
While intravenous immunoglobulin has aided in a variety of autoimmune-mediated
disorders, its efficacy in mycoplasma-mediated encephalitis treatment remains
unclear. In this patient case, reversal of both central and peripheral nervous
system symptoms after treatment with intravenous immunoglobulin suggested a
possible therapeutic benefit.