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2015 ; 2
(4
): 2329048X15609053
Nephropedia Template TP
gab.com Text
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English Wikipedia
A New Observation of an Atypical and Severe Variant of the Guillain-Barre
Syndrome in a Child: Remaining Challenges for Diagnosis, Nosologic
Classification, and Therapeutic Course
#MMPMID28503595
Pons L
; Manel V
; Ville D
; Javouhey E
; Bordet F
Child Neurol Open
2015[Oct]; 2
(4
): 2329048X15609053
PMID28503595
show ga
Guillain-Barré syndrome is a rare acute polyradiculoneuropathy. Several variants
and unusual presentations have been described, particularly in pediatrics. In
most cases, making an early diagnosis is challenging due to the treatments that
consist in the rapid administration of intravenous immunoglobulin or plasma
exchange. The authors present the case of a 7-year-old boy with an atypical and
severe axonal Guillain-Barré syndrome, associated with Mycoplasma pneumonia. When
he was admitted, febrile respiratory failure was the main focus, and then he
presented signs of acute polyneuropathy with cranial nerve palsy and brief
hyperreflexia. Mechanical ventilation was required for 48 days as well as 2
cycles of intravenous immunoglobulin. The authors describe all the medical
challenges that the authors encountered. This case highlights the fact that
respiratory distress can be the main clinical symptom in children. This delays
the establishment of a correct diagnosis, even more so when neurological
manifestations are abundant and unusual.