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10.1038/scsandc.2017.20

http://scihub22266oqcxt.onion/10.1038/scsandc.2017.20
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suck abstract from ncbi


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pmid28503326
      Spinal+Cord+Ser+Cases 2017 ; 3 (ä): 17020
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  • Incomplete paraplegia caused by extramedullary hematopoiesis in a patient with thalassemia intermedia #MMPMID28503326
  • Hisamud-Din N ; Mustafah NM ; Fauzi AA ; Hashim NM
  • Spinal Cord Ser Cases 2017[]; 3 (ä): 17020 PMID28503326 show ga
  • INTRODUCTION: Extramedullary hematopoiesis (EMH) is the production of blood cell precursors outside the bone marrow that occur in various hematological diseases. In patients with thalassemia intermedia, ineffective erythropoiesis drives compensatory EMH in the liver, pancreas, pleura, spleen, ribs and spine. CASE PRESENTATION: We describe a patient with thalassemia intermedia who presented with acute neurological symptoms caused by paraspinal EMH, which responded well to combination therapy of steroid, hypertransfusion, laminectomy and excision of pseudotumor and hydroxyurea therapy to boost the formation of fetal haemoglobin. DISCUSSION: Prompt recognition of EMH based on clinical presentation and typical radiological findings should be made. Early treatment is recommended to prevent irreversible damage to the spinal cord.
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