Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1186/s11658-017-0035-3 http://scihub22266oqcxt.onion/10.1186/s11658-017-0035-3 C5415841!5415841!28536635     free     free     free       Cell+Mol+Biol+Lett 2017 ; 22 (ä): ä Nephropedia Template TP {{tp|p=28536635|t=2017. The regulatory mechanisms of NG2/CSPG4 expression |pdf=|usr=}}{{28536635}} gab.com Text The regulatory mechanisms of NG2/CSPG4 expression JO: Cell Mol Biol Lett http://www.kidney.de/pget.php?&tw=1&pmid=28536635 #FOAvip Neuron-glial antigen 2 (NG2), also known as chondroitin sulphate proteoglycan 4 (CSPG4), is a surface type I transmembrane core proteoglycan that is crucially involved in cell survival, migration and angiogenesis. NG2 is frequently used as a marker for the identification and characterization of certain cell types, but little is known about the mechanisms regulating its expression. In this review, we provide evidence that the regulation of NG2 expression underlies inflammation and hypoxia and is mediated by methyltransferases, transcription factors, including Sp1, paired box (Pax) 3 and Egr-1, and the microRNA miR129-2. These regulatory factors crucially determine NG2-mediated cellular processes such as glial scar formation in the central nervous system (CNS) or tumor growth and metastasis. Therefore, they are potential targets for the establishment of novel NG2-based therapeutic strategies in the treatment of CNS injuries, cancer and other conditions of these types. Twit Text FOAVip The regulatory mechanisms of NG2/CSPG4 expression ????Cell Mol Biol Lett http://www.kidney.de/pget.php?&tw=1&pmid=28536635 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28536635 #FOAvip English Wikipedia <ref>{{Cite pmid|28536635}}</ref> The regulatory mechanisms of NG2/CSPG4 expression #MMPMID28536635 Ampofo E; Schmitt BM; Menger MD; Laschke MW Cell Mol Biol Lett 2017[]; 22 (ä): ä PMID28536635show ga Neuron-glial antigen 2 (NG2), also known as chondroitin sulphate proteoglycan 4 (CSPG4), is a surface type I transmembrane core proteoglycan that is crucially involved in cell survival, migration and angiogenesis. NG2 is frequently used as a marker for the identification and characterization of certain cell types, but little is known about the mechanisms regulating its expression. In this review, we provide evidence that the regulation of NG2 expression underlies inflammation and hypoxia and is mediated by methyltransferases, transcription factors, including Sp1, paired box (Pax) 3 and Egr-1, and the microRNA miR129-2. These regulatory factors crucially determine NG2-mediated cellular processes such as glial scar formation in the central nervous system (CNS) or tumor growth and metastasis. Therefore, they are potential targets for the establishment of novel NG2-based therapeutic strategies in the treatment of CNS injuries, cancer and other conditions of these types. äThe regulatory mechanisms of NG2/CSPG4 expression (epmc).pdf DeepDyve Pubget Overpricing