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10.1186/s13075-017-1297-x http://scihub22266oqcxt.onion/10.1186/s13075-017-1297-x C5414167!5414167 !28464909     free     free     free Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28464909 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Arthritis+Res+Ther 2017 ; 19 (1 ): 84 Nephropedia Template TP {{tp|p=28464909 |t=2017. Multicenter inception cohort of enthesitis-related arthritis: variation in disease characteristics and treatment approaches |pdf=|usr=}}{{28464909 }} gab.com Text Multicenter inception cohort of enthesitis-related arthritis: variation in disease characteristics and treatment approaches JO: Arthritis Res Ther http://www.kidney.de/pget.php?&tw=1&pmid=28464909 #FOAvip BACKGROUND: Enthesitis-related arthritis (ERA) is a specific subtype of juvenile idiopathic arthritis (JIA) defined according to the International League of Associations for Rheumatology (ILAR) criteria. We aimed to characterize the clinical features and treatment regimens in an inception cohort of children with ERA. METHODS: We performed a retrospective, cross-sectional, multicenter cohort study including subjects diagnosed with ERA between 1989 and 2012. Patients all fulfilled the ILAR criteria for ERA within 3 months of initial presentation to the rheumatology clinic. Differences in the prevalence of clinical criteria across study sites and by human leukocyte antigen (HLA)-B27 status were assessed using the Wilcoxon rank-sum or chi-square test, as appropriate. RESULTS: Two hundred thirty-four children met the inclusion criteria. Their median age at diagnosis was 11.6 years, and 59% were HLA-B27-positive. Sixty-nine percent had enthesitis and arthritis at the time of diagnosis. Seventy-eight percent had a pauciarticular onset. The prevalence of all ILAR criteria at diagnosis, except arthritis and acute anterior uveitis, differed significantly across sites (all p?<?0.01). Medication use varied significantly across sites for children with peripheral arthritis (p?<?0.001), but not for sacroiliitis or enthesitis only. Nonsteroidal anti-inflammatory drugs and disease-modifying antirheumatic drugs were the most commonly prescribed treatments, with anti-TNF agents primarily being initiation for sacroiliitis. HLA-B27 positivity was associated with male sex, higher active joint count, sacroiliitis, and higher disease activity at disease onset. CONCLUSIONS: The majority of children had a pauciarticular onset, and several statistically significant clinical differences based on HLA-B27 status were identified. The observed heterogeneity in clinical presentation across sites reflects either true differences in patient populations or differences in how the ILAR criteria are being applied. Twit Text FOAVip Multicenter inception cohort of enthesitis-related arthritis: variation in disease characteristics and treatment approaches ????Arthritis Res Ther http://www.kidney.de/pget.php?&tw=1&pmid=28464909 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28464909 #FOAvip English Wikipedia <ref>{{Cite pmid|28464909 }}</ref> Multicenter inception cohort of enthesitis-related arthritis: variation in disease characteristics and treatment approaches #MMPMID28464909 Gmuca S ; Xiao R ; Brandon TG ; Pagnini I ; Wright TB ; Beukelman T ; Morgan EM ; Weiss PF Arthritis Res Ther 2017[May]; 19 (1 ): 84 PMID28464909 show ga BACKGROUND: Enthesitis-related arthritis (ERA) is a specific subtype of juvenile idiopathic arthritis (JIA) defined according to the International League of Associations for Rheumatology (ILAR) criteria. We aimed to characterize the clinical features and treatment regimens in an inception cohort of children with ERA. METHODS: We performed a retrospective, cross-sectional, multicenter cohort study including subjects diagnosed with ERA between 1989 and 2012. Patients all fulfilled the ILAR criteria for ERA within 3 months of initial presentation to the rheumatology clinic. Differences in the prevalence of clinical criteria across study sites and by human leukocyte antigen (HLA)-B27 status were assessed using the Wilcoxon rank-sum or chi-square test, as appropriate. RESULTS: Two hundred thirty-four children met the inclusion criteria. Their median age at diagnosis was 11.6 years, and 59% were HLA-B27-positive. Sixty-nine percent had enthesitis and arthritis at the time of diagnosis. Seventy-eight percent had a pauciarticular onset. The prevalence of all ILAR criteria at diagnosis, except arthritis and acute anterior uveitis, differed significantly across sites (all p? |*Internationality [MESH] |Adolescent [MESH] |Anti-Inflammatory Agents, Non-Steroidal/*therapeutic use [MESH] |Antirheumatic Agents/*therapeutic use [MESH] |Arthritis, Juvenile/blood/*diagnosis/*drug therapy [MESH] |Child [MESH] |Cohort Studies [MESH] |Cross-Sectional Studies [MESH] |Female [MESH] |HLA-B27 Antigen/blood [MESH] |Humans [MESH] |Male [MESH] |Retrospective Studies [MESH]Multicenter inception cohort of enthesitis-related arthritis: variatio(epmc).pdf DeepDyve Pubget Overpricing