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10.1083/jcb.201609071

http://scihub22266oqcxt.onion/10.1083/jcb.201609071
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C5412568!5412568!28356327
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suck abstract from ncbi


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pmid28356327      J+Cell+Biol 2017 ; 216 (5): 1321-35
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  • The crossover conformational shift of the GTPase atlastin provides the energy driving ER fusion #MMPMID28356327
  • Winsor J; Hackney DD; Lee TH
  • J Cell Biol 2017[May]; 216 (5): 1321-35 PMID28356327show ga
  • The GTPase atlastin mediates homotypic membrane ER fusion through trans-dimerization between GTPase heads. Winsor et al. use a mutagenesis approach to show that, upon contact between atlastin heads, the proteins concurrently display GTP hydrolysis-catalyzed head-to-head dimerization and a crossover conformational shift, and these changes energize fusion.
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