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10.1083/jcb.201609022

http://scihub22266oqcxt.onion/10.1083/jcb.201609022
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C5412566!5412566!28404644
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suck abstract from ncbi


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pmid28404644      J+Cell+Biol 2017 ; 216 (5): 1357-69
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  • Preprotein mature domains contain translocase targeting signals that are essential for secretion #MMPMID28404644
  • Chatzi KE; Sardis MF; Tsirigotaki A; Koukaki M; ?o?tari? N; Konijnenberg A; Sobott F; Kalodimos CG; Karamanou S; Economou A
  • J Cell Biol 2017[May]; 216 (5): 1357-69 PMID28404644show ga
  • Secretory preproteins contain a mature domain fused to a signal peptide that targets the protein to the translocase, which mediates secretion. In this study, the authors show that the mature domains bear independent targeting signals (MTS) that consist of multiple, degenerate, interchangeable, linear or 3D hydrophobic stretches that are essential for proper secretion.
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