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10.3390/ijms18040717 http://scihub22266oqcxt.onion/10.3390/ijms18040717 C5412303!5412303!28350323     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Mol+Sci 2017 ; 18 (4): ä Nephropedia Template TP {{tp|p=28350323|t=2017. Extracellular Vesicles as Therapeutic Agents in Systemic Lupus Erythematosus |pdf=|usr=}}{{28350323}} gab.com Text Extracellular Vesicles as Therapeutic Agents in Systemic Lupus Erythematosus JO: Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=28350323 #FOAvip Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease that affects multiple organs. Currently, therapeutic molecules present adverse side effects and are only effective in some SLE patient subgroups. Extracellular vesicles (EV), including exosomes, microvesicles and apoptotic bodies, are released by most cell types, carry nucleic acids, proteins and lipids and play a crucial role in cell-to-cell communication. EVs can stimulate or suppress the immune responses depending on the context. In SLE, EVs can work as autoadjuvants, enhance immune complex formation and maintaining inflammation state. Over the last years, EVs derived from mesenchymal stem cells and antigen presenting cells have emerged as cell-free therapeutic agents to treat autoimmune and inflammatory diseases. In this review, we summarize the current therapeutic applications of extracellular vesicles to regulate immune responses and to ameliorate disease activity in SLE and other autoimmune disorders. Twit Text FOAVip Extracellular Vesicles as Therapeutic Agents in Systemic Lupus Erythematosus ????Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=28350323 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28350323 #FOAvip English Wikipedia <ref>{{Cite pmid|28350323}}</ref> Extracellular Vesicles as Therapeutic Agents in Systemic Lupus Erythematosus #MMPMID28350323 Perez-Hernandez J; Redon J; Cortes R Int J Mol Sci 2017[Apr]; 18 (4): ä PMID28350323show ga Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease that affects multiple organs. Currently, therapeutic molecules present adverse side effects and are only effective in some SLE patient subgroups. Extracellular vesicles (EV), including exosomes, microvesicles and apoptotic bodies, are released by most cell types, carry nucleic acids, proteins and lipids and play a crucial role in cell-to-cell communication. EVs can stimulate or suppress the immune responses depending on the context. In SLE, EVs can work as autoadjuvants, enhance immune complex formation and maintaining inflammation state. Over the last years, EVs derived from mesenchymal stem cells and antigen presenting cells have emerged as cell-free therapeutic agents to treat autoimmune and inflammatory diseases. In this review, we summarize the current therapeutic applications of extracellular vesicles to regulate immune responses and to ameliorate disease activity in SLE and other autoimmune disorders. äExtracellular Vesicles as Therapeutic Agents in Systemic Lupus Erythem(epmc).pdf DeepDyve Pubget Overpricing