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http://scihub22266oqcxt.onion/ C5411914!5411914 !28469771     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28469771 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28469771 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Am+J+Transl+Res 2017 ; 9 (4 ): 1641-1650 Nephropedia Template TP {{tp|p=28469771 |t=2017. Loss of PRRX1 induces epithelial-mesenchymal transition and cancer stem cell-like properties in A549 cells |pdf=|usr=}}{{28469771 }} gab.com Text Loss of PRRX1 induces epithelial-mesenchymal transition and cancer stem cell-like properties in A549 cells JO: Am J Transl Res http://www.kidney.de/pget.php?&tw=1&pmid=28469771 #FOAvip Epithelial-mesenchymal transition (EMT) plays crucial role in tumor metastasis and patient prognosis. Previous studies indicated that paired-related homeobox 1 (PRRX1), a newly identified EMT inducer, plays opposing roles in different tumor cell types. However, the function of PRRX1 in lung cancer has not been elucidated. In the present study, we observed that the expression level of PRRX1 was high in A549 cells, and a loss of PRRX1 induced EMT by regulating the EMT markers N-cadherin, E-cadherin and vimentin in A549 cells. This loss also distinctly affected cell morphology, migration and invasion. Moreover, a loss of PRRX1 increased the expression levels of cancer stem cell (CSC) markers and promoted the proliferation of these cells. These findings demonstrated that PRRX1 inhibits EMT and induces CSC-like properties in A549 cells. Twit Text FOAVip Loss of PRRX1 induces epithelial-mesenchymal transition and cancer stem cell-like properties in A549 cells ????Am J Transl Res http://www.kidney.de/pget.php?&tw=1&pmid=28469771 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28469771 #FOAvip English Wikipedia <ref>{{Cite pmid|28469771 }}</ref> Loss of PRRX1 induces epithelial-mesenchymal transition and cancer stem cell-like properties in A549 cells #MMPMID28469771 Zhu H ; Sun G Am J Transl Res 2017[]; 9 (4 ): 1641-1650 PMID28469771 show ga Epithelial-mesenchymal transition (EMT) plays crucial role in tumor metastasis and patient prognosis. Previous studies indicated that paired-related homeobox 1 (PRRX1), a newly identified EMT inducer, plays opposing roles in different tumor cell types. However, the function of PRRX1 in lung cancer has not been elucidated. In the present study, we observed that the expression level of PRRX1 was high in A549 cells, and a loss of PRRX1 induced EMT by regulating the EMT markers N-cadherin, E-cadherin and vimentin in A549 cells. This loss also distinctly affected cell morphology, migration and invasion. Moreover, a loss of PRRX1 increased the expression levels of cancer stem cell (CSC) markers and promoted the proliferation of these cells. These findings demonstrated that PRRX1 inhibits EMT and induces CSC-like properties in A549 cells. äLoss of PRRX1 induces epithelial-mesenchymal transition and cancer ste(epmc).pdf DeepDyve Pubget Overpricing