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10.1007/s13730-014-0109-2 http://scihub22266oqcxt.onion/10.1007/s13730-014-0109-2 C5411563!5411563!28509193     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       CEN+Case+Rep 2014 ; 3 (2): 158-61 Nephropedia Template TP {{tp|p=28509193|t=2014. Acute severe liver dysfunction induced by febuxostat in a patient undergoing hemodialysis |pdf=|usr=}}{{28509193}} gab.com Text Acute severe liver dysfunction induced by febuxostat in a patient undergoing hemodialysis JO: CEN Case Rep http://www.kidney.de/pget.php?&tw=1&pmid=28509193 #FOAvip A 58-year-old man with chronic kidney disease (CKD) was admitted to our hospital for hemodialysis (HD) therapy. He had been administered allopurinol (100 mg/day) before hospitalization, and we replaced it with febuxostat (10 mg/day), a new xanthine oxidase inhibitor. Levels of aspartate aminotransferase, alanine transaminase (ALT), and lactate dehydrogenase were within the normal ranges in the morning before febuxostat administration, but 6 h after administration, these parameters increased markedly to approximately 10 times the levels before administration. Although we stopped administering febuxostat, his serum potassium levels increased at a rate of 1 mmol/L every 12 h, and he had to undergo HD daily to lower the serum potassium levels. The levels of liver function test parameters peaked on the fourth hospital day (ALT, 1134 IU/L; AST, 1485 IU/L; and LDH, 1869 IU/L) and recovered to normal ranges on the 13th hospital day. In this case, febuxostat appeared to have a relationship with acute liver dysfunction in the clinical course. Therefore, it would be important to check liver function test parameters frequently after febuxostat initiation and also to initiate a lower than usual dose of febuxostat, especially in patients with CKD and those who are undergoing HD. Twit Text FOAVip Acute severe liver dysfunction induced by febuxostat in a patient undergoing hemodialysis ????CEN Case Rep http://www.kidney.de/pget.php?&tw=1&pmid=28509193 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28509193 #FOAvip English Wikipedia <ref>{{Cite pmid|28509193}}</ref> Acute severe liver dysfunction induced by febuxostat in a patient undergoing hemodialysis #MMPMID28509193 Ito K; Ueda Y; Miyazawa H; Kaku Y; Hirai K; Hoshino T; Nabata A; Mori H; Yoshida I; Ookawara S; Tabei K CEN Case Rep 2014[Nov]; 3 (2): 158-61 PMID28509193show ga A 58-year-old man with chronic kidney disease (CKD) was admitted to our hospital for hemodialysis (HD) therapy. He had been administered allopurinol (100 mg/day) before hospitalization, and we replaced it with febuxostat (10 mg/day), a new xanthine oxidase inhibitor. Levels of aspartate aminotransferase, alanine transaminase (ALT), and lactate dehydrogenase were within the normal ranges in the morning before febuxostat administration, but 6 h after administration, these parameters increased markedly to approximately 10 times the levels before administration. Although we stopped administering febuxostat, his serum potassium levels increased at a rate of 1 mmol/L every 12 h, and he had to undergo HD daily to lower the serum potassium levels. The levels of liver function test parameters peaked on the fourth hospital day (ALT, 1134 IU/L; AST, 1485 IU/L; and LDH, 1869 IU/L) and recovered to normal ranges on the 13th hospital day. In this case, febuxostat appeared to have a relationship with acute liver dysfunction in the clinical course. Therefore, it would be important to check liver function test parameters frequently after febuxostat initiation and also to initiate a lower than usual dose of febuxostat, especially in patients with CKD and those who are undergoing HD. äAcute severe liver dysfunction induced by febuxostat in a patient unde(epmc).pdf DeepDyve Pubget Overpricing