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2013 ; 32
(1
): 51-66
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A fully Bayesian application of the Copas selection model for publication bias
extended to network meta-analysis
#MMPMID22806991
Mavridis D
; Sutton A
; Cipriani A
; Salanti G
Stat Med
2013[Jan]; 32
(1
): 51-66
PMID22806991
show ga
The Copas parametric model is aimed at exploring the potential impact of
publication bias via sensitivity analysis, by making assumptions regarding the
probability of publication of individual studies related to the standard error of
their effect sizes. Reviewers often have prior assumptions about the extent of
selection in the set of studies included in a meta-analysis. However, a Bayesian
implementation of the Copas model has not been studied yet. We aim to present a
Bayesian selection model for publication bias and to extend it to the case of
network meta-analysis where each treatment is compared either with placebo or
with a reference treatment creating a star-shaped network. We take advantage of
the greater flexibility offered in the Bayesian context to incorporate in the
model prior information on the extent and strength of selection. To derive prior
distributions, we use both external data and an elicitation process of expert
opinion.