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10.1093/rheumatology/kew427 http://scihub22266oqcxt.onion/10.1093/rheumatology/kew427 C5410978!5410978!28375453     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Rheumatology+(Oxford) 2017 ; 56 (Suppl 1): i55-66 Nephropedia Template TP {{tp|p=28375453|t=2017. Pathways leading to an immunological disease: systemic lupus erythematosus |pdf=|usr=}}{{28375453}} gab.com Text Pathways leading to an immunological disease: systemic lupus erythematosus JO: Rheumatology (Oxford) http://www.kidney.de/pget.php?&tw=1&pmid=28375453 #FOAvip SLE is a chronic autoimmune disease caused by perturbations of the immune system. The clinical presentation is heterogeneous, largely because of the multiple genetic and environmental factors that contribute to disease initiation and progression. Over the last 60 years, there have been a number of significant leaps in our understanding of the immunological mechanisms driving disease processes. We now know that multiple leucocyte subsets, together with inflammatory cytokines, chemokines and regulatory mediators that are normally involved in host protection from invading pathogens, contribute to the inflammatory events leading to tissue destruction and organ failure. In this broad overview, we discuss the main pathways involved in SLE and highlight new findings. We describe the immunological changes that characterize this form of autoimmunity. The major leucocytes that are essential for disease progression are discussed, together with key mediators that propagate the immune response and drive the inflammatory response in SLE. Twit Text FOAVip Pathways leading to an immunological disease: systemic lupus erythematosus ????Rheumatology (Oxford) http://www.kidney.de/pget.php?&tw=1&pmid=28375453 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28375453 #FOAvip English Wikipedia <ref>{{Cite pmid|28375453}}</ref> Pathways leading to an immunological disease: systemic lupus erythematosus #MMPMID28375453 Zharkova O; Celhar T; Cravens PD; Satterthwaite AB; Fairhurst AM; Davis LS Rheumatology (Oxford) 2017[Apr]; 56 (Suppl 1): i55-66 PMID28375453show ga SLE is a chronic autoimmune disease caused by perturbations of the immune system. The clinical presentation is heterogeneous, largely because of the multiple genetic and environmental factors that contribute to disease initiation and progression. Over the last 60 years, there have been a number of significant leaps in our understanding of the immunological mechanisms driving disease processes. We now know that multiple leucocyte subsets, together with inflammatory cytokines, chemokines and regulatory mediators that are normally involved in host protection from invading pathogens, contribute to the inflammatory events leading to tissue destruction and organ failure. In this broad overview, we discuss the main pathways involved in SLE and highlight new findings. We describe the immunological changes that characterize this form of autoimmunity. The major leucocytes that are essential for disease progression are discussed, together with key mediators that propagate the immune response and drive the inflammatory response in SLE. äPathways leading to an immunological disease: systemic lupus erythemat(epmc).pdf DeepDyve Pubget Overpricing