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10.1021/acsomega.7b00053 http://scihub22266oqcxt.onion/10.1021/acsomega.7b00053 C5410656!5410656!28474009     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       ACS+Omega 2017 ; 2 (4): 1302-8 Nephropedia Template TP {{tp|p=28474009|t=2017. Hamming Distance as a Concept in DNA Molecular Recognition |pdf=|usr=}}{{28474009}} gab.com Text Hamming Distance as a Concept in DNA Molecular Recognition JO: ACS Omega http://www.kidney.de/pget.php?&tw=1&pmid=28474009 #FOAvip DNA microarrays constitute an in vitro example system of a highly crowded molecular recognition environment. Although they are widely applied in many biological applications, some of the basic mechanisms of the hybridization processes of DNA remain poorly understood. On a microarray, cross-hybridization arises from similarities of sequences that may introduce errors during the transmission of information. Experimentally, we determine an appropriate distance, called minimum Hamming distance, in which the sequences of a set differ. By applying an algorithm based on a graph-theoretical method, we find large orthogonal sets of sequences that are sufficiently different not to exhibit any cross-hybridization. To create such a set, we first derive an analytical solution for the number of sequences that include at least four guanines in a row for a given sequence length and eliminate them from the list of candidate sequences. We experimentally confirm the orthogonality of the largest possible set with a size of 23 for the length of 7. We anticipate our work to be a starting point toward the study of signal propagation in highly competitive environments, besides its obvious application in DNA high throughput experiments. Twit Text FOAVip Hamming Distance as a Concept in DNA Molecular Recognition ????ACS Omega http://www.kidney.de/pget.php?&tw=1&pmid=28474009 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28474009 #FOAvip English Wikipedia <ref>{{Cite pmid|28474009}}</ref> Hamming Distance as a Concept in DNA Molecular Recognition #MMPMID28474009 Mohammadi-Kambs M; Hölz K; Somoza MM; Ott A ACS Omega 2017[Apr]; 2 (4): 1302-8 PMID28474009show ga DNA microarrays constitute an in vitro example system of a highly crowded molecular recognition environment. Although they are widely applied in many biological applications, some of the basic mechanisms of the hybridization processes of DNA remain poorly understood. On a microarray, cross-hybridization arises from similarities of sequences that may introduce errors during the transmission of information. Experimentally, we determine an appropriate distance, called minimum Hamming distance, in which the sequences of a set differ. By applying an algorithm based on a graph-theoretical method, we find large orthogonal sets of sequences that are sufficiently different not to exhibit any cross-hybridization. To create such a set, we first derive an analytical solution for the number of sequences that include at least four guanines in a row for a given sequence length and eliminate them from the list of candidate sequences. We experimentally confirm the orthogonality of the largest possible set with a size of 23 for the length of 7. We anticipate our work to be a starting point toward the study of signal propagation in highly competitive environments, besides its obvious application in DNA high throughput experiments. äHamming Distance as a Concept in DNA Molecular Recognition (epmc).pdf DeepDyve Pubget Overpricing