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10.1038/nmeth.4236

http://scihub22266oqcxt.onion/10.1038/nmeth.4236
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C5410170!5410170!28346451
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suck abstract from ncbi


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pmid28346451      Nat+Methods 2017 ; 14 (5): 483-6
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  • SC3 - consensus clustering of single-cell RNA-Seq data #MMPMID28346451
  • Kiselev VY; Kirschner K; Schaub MT; Andrews T; Yiu A; Chandra T; Natarajan KN; Reik W; Barahona M; Green AR; Hemberg M
  • Nat Methods 2017[May]; 14 (5): 483-6 PMID28346451show ga
  • Single-cell RNA-seq (scRNA-seq) enables a quantitative cell-type characterisation based on global transcriptome profiles. We present Single-Cell Consensus Clustering (SC3), a user-friendly tool for unsupervised clustering which achieves high accuracy and robustness by combining multiple clustering solutions through a consensus approach. We demonstrate that SC3 is capable of identifying subclones based on the transcriptomes from neoplastic cells collected from patients.
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