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10.1016/j.nantod.2015.04.004 http://scihub22266oqcxt.onion/10.1016/j.nantod.2015.04.004 C5409525!5409525!28458718     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nano+Today 2015 ; 10 (3): 397-409 Nephropedia Template TP {{tp|p=28458718|t=2015. Cell-derived vesicles for drug therapy and diagnostics: opportunities and challenges |pdf=|usr=}}{{28458718}} gab.com Text Cell-derived vesicles for drug therapy and diagnostics: opportunities and challenges JO: Nano Today http://www.kidney.de/pget.php?&tw=1&pmid=28458718 #FOAvip Extracellular vesicles are small lipid-based membrane-bound entities shed by cells under both physiological and pathological conditions. Their discovery as intercellular communicators through transfer of nucleic acid- and protein-based cargos between cells locally and at distance in a highly specific manner has created recent excitement. The information they transport and their composition may vary depending on the cell of origin as well as the eliciting stimulus. Such sensitive changes in vesicle characteristics hold significant promise for the improved diagnosis of pathological conditions, including infections and neoplastic lesions in a minimally invasive way. Similarly, these cell-derived vesicles exhibit promising characteristics that could enhance drug targeting efficiencies. Recent developments in the field have aimed at studying EVs as novel drug carriers due to their natural composition, biological function and selective cell interaction. In this review, we discuss new research avenues in diagnostics and drug therapy based on extracellular vesicles. We show how cell-derived vesicles can be harvested and engineered to meet application-specific design requirements. We finally discuss potential risks encountered when translating extracellular vesicle based approaches into (pre)clinical applications. Twit Text FOAVip Cell-derived vesicles for drug therapy and diagnostics: opportunities and challenges ????Nano Today http://www.kidney.de/pget.php?&tw=1&pmid=28458718 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28458718 #FOAvip English Wikipedia <ref>{{Cite pmid|28458718}}</ref> Cell-derived vesicles for drug therapy and diagnostics: opportunities and challenges #MMPMID28458718 Fuhrmann G; Herrmann IK; Stevens MM Nano Today 2015[Jun]; 10 (3): 397-409 PMID28458718show ga Extracellular vesicles are small lipid-based membrane-bound entities shed by cells under both physiological and pathological conditions. Their discovery as intercellular communicators through transfer of nucleic acid- and protein-based cargos between cells locally and at distance in a highly specific manner has created recent excitement. The information they transport and their composition may vary depending on the cell of origin as well as the eliciting stimulus. Such sensitive changes in vesicle characteristics hold significant promise for the improved diagnosis of pathological conditions, including infections and neoplastic lesions in a minimally invasive way. Similarly, these cell-derived vesicles exhibit promising characteristics that could enhance drug targeting efficiencies. Recent developments in the field have aimed at studying EVs as novel drug carriers due to their natural composition, biological function and selective cell interaction. In this review, we discuss new research avenues in diagnostics and drug therapy based on extracellular vesicles. We show how cell-derived vesicles can be harvested and engineered to meet application-specific design requirements. We finally discuss potential risks encountered when translating extracellular vesicle based approaches into (pre)clinical applications. äCell-derived vesicles for drug therapy and diagnostics: opportunities (epmc).pdf DeepDyve Pubget Overpricing